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01

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Tepoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Orthopoxviruses.

Product Name : Tepoxx

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

January 02, 2025

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Tpoxx (tecovirimat) is an antiviral drug candidate that targets orthopoxvirus VP37 envelope wrapping protein. It is being evaluated for the treatment of mpox.

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

December 10, 2024

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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03

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : The agreement aims for the procurement of Tpoxx (tecovirimat), an antiviral, approved in the US and Canada for the treatment of smallpox and authorized in EU and the UK for smallpox, mpox and cowpox.

Product Name : Tpoxx

Product Type : Small molecule

Upfront Cash : Undisclosed

August 21, 2024

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Approved

Sponsor : U.S. Department of Defense

Deal Size : Undisclosed

Deal Type : Agreement

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04

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Tpoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Monkeypox Virus.

Product Name : Tpoxx

Product Type : Small molecule

Upfront Cash : Not Applicable

August 15, 2024

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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05

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : The agreement aims to expand access to Tpoxx (tecovirimat), a novel small-molecule drug for the treatment of smallpox, to the member states in the ASEAN.

Product Name : Tpoxx

Product Type : Small molecule

Upfront Cash : Undisclosed

June 17, 2024

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Approved

Sponsor : ASEAN

Deal Size : Undisclosed

Deal Type : Divestment

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06

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : SIGA will lead international promotions for oral TPOXX, an FDA-approved drug for smallpox, while maintaining its contractual relationship with Meridian to ensure continuity for key customers.

Product Name : Tpoxx

Product Type : Small molecule

Upfront Cash : Undisclosed

April 01, 2024

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Approved

Sponsor : SIGA Technologies

Deal Size : Undisclosed

Deal Type : Agreement

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07

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : TPOXX (tecovirimat), also known as tecovirimat and ST-246®, an orally administered and IV formulation antiviral drug for the treatment of human smallpox disease caused by variola virus.

Product Name : Tpoxx

Product Type : Small molecule

Upfront Cash : Not Applicable

October 12, 2022

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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08

NIHR

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BePharma
Not Confirmed

NIHR

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BePharma
Not Confirmed

Details : Tecovirimat (also known as TPOXX®) prevents the virus from leaving infected cells, stopping its spread within the body for monkeypox based on promising results from initial studies in animals and evidence of safety in healthy human volunteers.

Product Name : Tpoxx

Product Type : Small molecule

Upfront Cash : Not Applicable

August 23, 2022

Lead Product(s) : Tecovirimat

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Preclinical

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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09

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : The Company has also demonstrated the ability of NV-387 to encapsulate and improve the pharmacokinetics and pharmacodynamics of a very difficult drug, namely remdesivir, that is formulated in a cyclodextrin-based formulation at present (Veklury® Gilead)...

Product Name : NV-387

Product Type : Small molecule

Upfront Cash : Not Applicable

August 04, 2022

Lead Product(s) : Tecovirimat,NV-387

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Preclinical

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : TPOXX is a powerful antiviral drug to vaccinia and allows the safe use of higher doses of vaccinia vectors, there is also the potential it could increase immunotherapeutic outcomes.

Product Name : Undisclosed

Product Type : Large molecule

Upfront Cash : Undisclosed

July 15, 2022

Lead Product(s) : Vaccinia-based Cancer Therapy,Tecovirimat

Therapeutic Area : Oncology

Highest Development Status : Preclinical

Sponsor : KaliVir Immunotherapeutics

Deal Size : Undisclosed

Deal Type : Collaboration

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