Details : Tenalisib (RP6530, selective dual PI3K d/γ inhibitor with additional SIK3 inhibitory activity) showed encouraging results with a clinical benefit rate (CBR) of 57.5% from an ongoing phase II trial in patients with locally advanced or metastatic HR+/HER2...
Product Name : RP6530
Product Type : Small molecule
Upfront Cash : Not Applicable
September 09, 2022
Lead Product(s) : Tenalisib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Tenalisib (RP6530) is a highly selective and orally active dual PI3K delta/gamma inhibitor with efficient translation of activity through enzyme, cell, and whole blood-based studies.
Product Name : RP6530
Product Type : Small molecule
Upfront Cash : Not Applicable
January 22, 2021
Lead Product(s) : Tenalisib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tenalisib,Romidepsin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Rhizen Presents Tenalisib + Romidepsin Phase I/II Data in R/R T-cell Lymphoma
Details : RP6530 (tenalisib) is a highly selective next generation orally active dual PI3K δ/γ inhibitor being investigated with Romidepsin for relapsed/refractory T-Cell lymphoma.
Product Name : RP6530
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 05, 2020
Lead Product(s) : Tenalisib,Romidepsin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Curon obtains the exclusive development and commercialization rights of Tenalisib for Greater China across all oncology indications, and will lead the clinical development in that territory.
Product Name : RP6530
Product Type : Small molecule
Upfront Cash : Undisclosed
October 12, 2020
Lead Product(s) : Tenalisib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Single-agent Tenalisib was well tolerated with a good overall response rate (ORR) in both peripheral and cutaneous T-cell Lymphoma patients (PTCL and CTCL).
Product Name : RP6530
Product Type : Small molecule
Upfront Cash : Not Applicable
September 24, 2020
Lead Product(s) : Tenalisib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable