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    [{"orgOrder":0,"company":"Tenaya Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"AAV-Gene Therapy","moa":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Preclinical","graph3":"Tenaya Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Tenaya Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Tenaya Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Tenaya Therapeutics","sponsor":"RTW Investments","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Series C Financing","leadProduct":"AAV-gene therapy","moa":"MYBPC3 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                            01

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-401

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Doses First RIDGE™-1 Phase 1b Patient for PKP2-Associated Cardiomyopathy

                            Details : TN-401 is an investigational AAV9-based gene therapy. It is being developed for the treatment of ARVC due to mutations in the PKP2 gene.

                            Brand Name : TN-401

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 25, 2024

                            Lead Product(s) : TN-401

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Shares Updates on TN-201 Gene Therapy for MYBPC3 HCM

                            Details : TN-201 is being developed for the potential treatment of MYBPC3-associated hypertrophic cardiomyopathy (HCM), a condition caused by insufficient levels of myosin-binding protein C (MyBP-C)

                            Brand Name : TN-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 17, 2024

                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-401

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Announces FDA Clearance to Begin Clinical Testing of TN-401 Gene Therapy for the Treatment...

                            Details : TN-401 is an investigational adeno-associated virus serotype 9 (AAV9)-based gene therapy being developed for the treatment of ARVC due to disease causing variants in the PKP2 gene.

                            Brand Name : TN-401

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 26, 2023

                            Lead Product(s) : TN-401

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Doses First Patient in the MyPeak-1™ Phase 1b Clinical Trial of TN-201 for the Treatment...

                            Details : TN-201 is designed to deliver a fully functional MYBPC3 gene to restore normal levels of myosin-binding protein, which regulates the contraction and relaxation of the heart muscle. It is being investigated for MYBPC3-associated hypertrophic cardiomyopath...

                            Brand Name : TN-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 05, 2023

                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Receives FDA Fast Track Designation for TN-201

                            Details : TN-201 is designed to deliver a fully functional MYBPC3 gene to restore normal levels of myosin-binding protein, which regulates the contraction and relaxation of the heart muscle. It is being investigated for MYBPC3-associated hypertrophic cardiomyopath...

                            Brand Name : TN-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            May 02, 2023

                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Announces TN-201 IND Clearance and Anticipated 2023 Milestones

                            Details : TN-201 is an adeno-associated virus based investigational gene therapy designed to deliver fully functional MYBPC3 gene to restore its normal levels thereby potentially halt disease progression and reverse the course of genetic HCM after a single treatme...

                            Brand Name : TN-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 09, 2023

                            Lead Product(s) : TN-201

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-401

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Receives Orphan Drug Designation from the U.S. Food and Drug Administration for its Gene T...

                            Details : TN-401 is an AAV-based gene therapy for treatment of genetic ARVC caused by Plakophilin-2 gene mutations can cause severe disease, including enlargement of right ventricle in affected individuals, cardiac dysfunction, significant arrhythmia and sudden ca...

                            Brand Name : TN-401

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 28, 2022

                            Lead Product(s) : TN-401

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-201

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Morgan Stanley

                            Deal Size : $75.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Announces Closing of Public Offering

                            Details : TN-201 is a potentially curative gene therapy intended to address genetic hypertrophic cardiomyopathy (gHCM) caused by mutations in the Myosin Binding Protein C3 (MYBPC3) gene, that is currently in IND-enabling studies.

                            Brand Name : TN-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 21, 2022

                            Lead Product(s) : TN-201

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Morgan Stanley

                            Deal Size : $75.0 million

                            Deal Type : Public Offering

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                            09

                            Tenaya Therapeutics

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                            Lead Product(s) : TN-301

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Piper Sandler

                            Deal Size : $75.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Tenaya Therapeutics Announces Pricing of Public Offering

                            Details : TN-301 (previously named TYA-11631) is a small molecule HDAC6 inhibitor initially being developed by Tenaya for the potential treatment of heart failure with preserved ejection fraction (HFpEF).

                            Brand Name : TN-301

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 17, 2022

                            Lead Product(s) : TN-301

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Piper Sandler

                            Deal Size : $75.0 million

                            Deal Type : Public Offering

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                            Tenaya Therapeutics

                            U.S.A arrow
                            Duphat
                            Not Confirmed

                            Tenaya Therapeutics

                            U.S.A arrow
                            Duphat
                            Not Confirmed
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                            Lead Product(s) : TN-201

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Morgan Stanley

                            Deal Size : $75.0 million

                            Deal Type : Public Offering

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                            Tenaya Therapeutics Announces Proposed Public Offering

                            Details : TN-201 is a potentially curative gene therapy intended to address genetic hypertrophic cardiomyopathy (gHCM) caused by mutations in the Myosin Binding Protein C3 (MYBPC3) gene, that is currently in IND-enabling studies.

                            Brand Name : TN-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 16, 2022

                            Lead Product(s) : TN-201

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Morgan Stanley

                            Deal Size : $75.0 million

                            Deal Type : Public Offering

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