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    [{"orgOrder":0,"company":"Lupin Ltd","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"INDIA","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Emtricitabine","moa":"||HIV-1 reverse transcriptase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Lupin Ltd","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lupin Ltd \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Lupin Ltd \/ Inapplicable"},{"orgOrder":0,"company":"Lupin Ltd","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"INDIA","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Tenofovir Alafenamide","moa":"DNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Lupin Ltd","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lupin Ltd \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Lupin Ltd \/ Inapplicable"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"CHAI","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Partnership","leadProduct":"Emtricitabine","moa":"||HIV-1 reverse transcriptase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Gilead Sciences \/ CHAI","highestDevelopmentStatusID":"15","companyTruncated":"Gilead Sciences \/ CHAI"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tenofovir Alafenamide","moa":"DNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Gilead Sciences \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Gilead Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Arrowhead Pharmaceuticals","sponsor":"Johnson & Johnson Innovative Medicine","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"JNJ-3989","moa":"||HBsAg","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Arrowhead Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Arrowhead Pharmaceuticals \/ Johnson & Johnson Innovative Medicine","highestDevelopmentStatusID":"8","companyTruncated":"Arrowhead Pharmaceuticals \/ Johnson & Johnson Innovative Medicine"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tenofovir Alafenamide","moa":"DNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Gilead Sciences \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Gilead Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Tenofovir Alafenamide","moa":"DNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Gilead Sciences \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Gilead Sciences \/ Inapplicable"}]

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    Tenofovir Alafenamide

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                            01

                            Lupin Ltd

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                            Lupin Ltd

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                            Lead Product(s) : Emtricitabine,Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lupin receives US FDA tentative marketing approval for generic Descovy tablets

                            Details : Emtricitabine & tenofovir alafenamide is a generic equivalent of Descovy. This combination is NRT-inhibitor. It is indicated for HIV-1 Infection in adults & pediatric patients.

                            Product Name : Descovy-Generic

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 31, 2024

                            Lead Product(s) : Emtricitabine,Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Gilead Sciences

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                            BioTrinity 2025
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                            Gilead Sciences

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                            BioTrinity 2025
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                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Expands Gilead's Vemlidy Indication To Treat Chronic HBV in Pediatric Patients

                            Details : Vemlidy (tenofovir alafenamide) is approved for chronic hepatitis B in pediatric patients (6+ years) with compensated liver disease.

                            Product Name : Vemlidy

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 28, 2024

                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Gilead Sciences

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                            BioTrinity 2025
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                            Gilead Sciences

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                            BioTrinity 2025
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                            Lead Product(s) : Emtricitabine,Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : CHAI

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Gilead Partners with CHAI and Penta to Improve Treatment and Adherence Rates Among Children with HIV in Low an...

                            Details : The partnership aims to accelerate the development of an investigational dispersible pediatric formulation containing Descovy (emtricitabine) and tenofovir alafenamide (F/TAF).

                            Product Name : Descovy

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            July 13, 2023

                            Lead Product(s) : Emtricitabine,Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : CHAI

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            04

                            Lupin Ltd

                            India arrow
                            BioTrinity 2025
                            Not Confirmed

                            Lupin Ltd

                            India arrow
                            BioTrinity 2025
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                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lupin Receives Approval from USFDA for Tenofovir Alafenamide Tablets

                            Details : Tenofovir alafenamide accumulates more in peripheral blood mononuclear cells compared to red blood cells. Once activated, it acts with different mechanisms including the inhibition of viral polymerase, causing chain termination and the inhibition of vira...

                            Product Name : Vemlidy-Generic

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 31, 2023

                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Gilead Sciences

                            U.S.A arrow
                            BioTrinity 2025
                            Not Confirmed

                            Gilead Sciences

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                            BioTrinity 2025
                            Not Confirmed
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                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gilead to Present Latest Data From Across Liver Disease Development Programs at the International Liver Congre...

                            Details : In HBV, data presented will highlight the long-term results of switching to Vemlidy® (tenofovir alafenamide 25 mg, TAF) for HBV prophylaxis in post-liver transplant patients with chronic kidney disease, providing sustained improvements in bone and renal...

                            Product Name : Vemlidy

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 21, 2022

                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Gilead Sciences

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                            BioTrinity 2025
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                            Gilead Sciences

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                            BioTrinity 2025
                            Not Confirmed
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                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            U.S. Food and Drug Administration Approves Vemlidy® (tenofovir alafenamide) for Treatment of Chronic Hepatiti...

                            Details : Vemlidy (tenofovir alafenamide) is a novel, targeted prodrug of tenofovir that was previously approved by the FDA in 2016 as a once-daily treatment for adults with chronic HBV infection with compensated liver disease.

                            Product Name : Vemlidy

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 11, 2022

                            Lead Product(s) : Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Arrowhead Pharmaceuticals

                            U.S.A arrow
                            BioTrinity 2025
                            Not Confirmed

                            Arrowhead Pharmaceuticals

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                            BioTrinity 2025
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                            Lead Product(s) : JNJ-3989,Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Johnson & Johnson Innovative Medicine

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Arrowhead Pharmaceuticals to Participate in Upcoming April 2022 Conferences

                            Details : JNJ-3989 is a sub-cutaneous, ribonucleic acid interference (RNAi) therapy candidate which is designed to silence all HBV gene products and intervenes upstream of the reverse transcription process where current standard-of-care nucleotide and nucleoside a...

                            Product Name : JNJ-3989

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            January 04, 2022

                            Lead Product(s) : JNJ-3989,Tenofovir Alafenamide

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Johnson & Johnson Innovative Medicine

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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