Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase II
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The results from the Phase 2 GUARD trial of Angion’s ANG-3777 in patients undergoing cardiac surgery involving cardiopulmonary bypass at risk for developing acute kidney injury.
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 09, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase II
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ANG-3777 is a small molecule designed to mimic the biological activity of hepatocyte growth factor (HGF), trial did not meet its primary endpoint of percentage increase in serum creatinine based upon the area under the curve (AUC).
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 09, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The overall safety profile of ANG-3777 in this trial was consistent with the overall experience in its clinical development program and consistent with the published literature in this patient population.
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 26, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : $30.0 million
Deal Type : Licensing Agreement
Vifor Pharma and Angion Sign License Agreement for ANG-3777 in Nephrology Indications
Details : Under the terms of the agreement, Vifor Pharma will receive an exclusive global license, excluding China, Taiwan, Hong Kong and Macau, for all ANG-3777 nephrology indications.
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : $30.0 million
November 09, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : $30.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Terevalefim
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Phase 2 trial is a multicenter, prospective, randomized, double-blind, placebo-controlled trial to assess safety and efficacy of ANG-3777 in patients hospitalized with confirmed COVID-19 pneumonia.
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 08, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Company is going to discuss the effect of ANG-3777 on Hepatocyte Growth Factor Receptor c-MET Signaling.
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 29, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Angion Announces Publication of ANG-3777 Phase 2 Results in the Scientific Journal Transplantation
Details : The publication details the results of the administration of ANG-3777 in patients who have undergone deceased-donor kidney transplantation and had signs of kidney injury.
Brand Name : ANG-3777
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 05, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
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