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    [{"orgOrder":0,"company":"The University of Pittsburgh School of Medicine","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Ab8","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"The University of Pittsburgh School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"The University of Pittsburgh School of Medicine \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"The University of Pittsburgh School of Medicine \/ Not Applicable"},{"orgOrder":0,"company":"The University of Pittsburgh School of Medicine","sponsor":"Astellas Pharma","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene 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Medicine","sponsor":"Genprex","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Licensing Agreement","leadProduct":"GPX-002","moa":"","graph1":"Endocrinology","graph2":"Preclinical","graph3":"The University of Pittsburgh School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"","sponsorNew":"The University of Pittsburgh School of Medicine \/ Genprex","highestDevelopmentStatusID":"4","companyTruncated":"The University of Pittsburgh School of Medicine \/ Genprex"},{"orgOrder":0,"company":"The University of Pittsburgh School of Medicine","sponsor":"Genprex","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Licensing Agreement","leadProduct":"GPX-002","moa":"","graph1":"Endocrinology","graph2":"Preclinical","graph3":"The University of Pittsburgh School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"","sponsorNew":"The University of Pittsburgh School of Medicine \/ University of Pittsburgh","highestDevelopmentStatusID":"4","companyTruncated":"The University of Pittsburgh School of Medicine \/ University of Pittsburgh"},{"orgOrder":0,"company":"The University of Pittsburgh School of Medicine","sponsor":"Genprex","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Licensing Agreement","leadProduct":"GPX-002","moa":"","graph1":"Endocrinology","graph2":"Preclinical","graph3":"The University of Pittsburgh School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"","sponsorNew":"The University of Pittsburgh School of Medicine \/ Genprex","highestDevelopmentStatusID":"4","companyTruncated":"The University of Pittsburgh School of Medicine \/ Genprex"}]

    Find Clinical Drug Pipeline Developments & Deals by The University of Pittsburgh School of Medicine

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                            01

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : GPX-002

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Sponsor : Genprex

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Genprex Signs Exclusive License to Additional Diabetes Technology with the University of Pittsburgh

                            Details : Under the agreement, Genprex gains a worldwide, exclusive license to a patent application and related technology and a worldwide, non-exclusive license to use certain related know-how, all related to a gene therapy, GPX-002, for both Type 1 and Type 2 di...

                            Brand Name : GPX-002

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 18, 2023

                            Lead Product(s) : GPX-002

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Sponsor : Genprex

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : GPX-002

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Recipient : Genprex

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Genprex Signs Exclusive License to Additional Diabetes Technology with the University of Pittsburgh

                            Details : University of Pittsburgh grants Genprex a preclinical technology that transforms macrophages, complementary to the GPX-002 diabetes technology. Novel infusion process uses an endoscope and an AAV vector with a glucagon promoter to deliver the Pdx1 + MafA...

                            Brand Name : GPX-002

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 05, 2023

                            Lead Product(s) : GPX-002

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Recipient : Genprex

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : GPX-002

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Sponsor : Genprex

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Genprex Strengthens Diabetes Gene Therapy Program with License of Additional Technology from University of Pit...

                            Details : Diabetic mice studies have shown that GPX-002, a gene therapy for diabetes, restored normal blood glucose levels for an extended period of time, which could translate to decades in humans.

                            Brand Name : GPX-002

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            December 15, 2022

                            Lead Product(s) : GPX-002

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Sponsor : Genprex

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            04

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : Denileukin Diftitox,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Citius Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Citius Pharmaceuticals Announces a Clinical Collaboration with the University of Pittsburgh to Evaluate T-reg ...

                            Details : Preclinical research in a syngeneic solid tumor mouse model shows that I/ONTAK (E7777 or denileukin diftitox) enhances anti-tumor activity and significantly extends survival benefit of anti-PD-1 therapy.

                            Brand Name : I/ONTAK

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            September 22, 2022

                            Lead Product(s) : Denileukin Diftitox,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Citius Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : SNAP-CAR T Cell Therapy,Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Coeptis Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Coeptis Therapeutics Enters Exclusive License Agreement with University of Pittsburgh for Rights to SNAP-CAR, ...

                            Details : Current SNAP-CAR T therapies are designed to target specific tumor antigens that correspond to a specific cancer indication. This approach has proven effective in certain cancer types but limits the applicability of those CAR T therapies.

                            Brand Name : SNAP-CAR T Cell Therapy

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 21, 2022

                            Lead Product(s) : SNAP-CAR T Cell Therapy,Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Coeptis Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            06

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : nanobody

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Low Doses of Inhalable 'nanobody' Fights Off Covid in Hamsters

                            Details : The treatment, dubbed PiN-21, could offer an affordable, needle-free option for treating early infections of SARS-CoV-2—the novel coronavirus behind COVID.

                            Brand Name : PiN-21

                            Molecule Type : Undisclosed

                            Upfront Cash : Not Applicable

                            May 26, 2021

                            Lead Product(s) : nanobody

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : AAV-based gene therapy

                            Therapeutic Area : Ophthalmology

                            Study Phase : Discovery

                            Sponsor : Astellas Pharma

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Astellas, University of Pittsburgh Enter Research Collaboration for Dry Age-Related Macular Degeneration Treat...

                            Details : Cell Biology and Developmental Biology in University of Pittsburgh School of Medicine and Astellas will work jointly to evaluate and optimize the drug candidates with an aim to provide new treatment options to help recover and maintain vision in dry AMD ...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 24, 2020

                            Lead Product(s) : AAV-based gene therapy

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Discovery

                            Sponsor : Astellas Pharma

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            The University of Pittsburgh School of Medicine

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                            The University of Pittsburgh School of Medicine

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                            Lead Product(s) : Ab8

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pitt Scientists Discover Tiny Antibody Component That is Highly Effective in Preventing and Treating SARS-CoV-...

                            Details : The researchers reported in the journal Cell that Ab8 is highly effective in preventing and treating SARS-CoV-2 infection in mice and hamsters. In mice and hamsters, Ab8 proved effective in preventing and treating the disease; the journal Cell published ...

                            Brand Name : Ab8

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 14, 2020

                            Lead Product(s) : Ab8

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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