Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : GPX-002
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Genprex
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Genprex Signs Exclusive License to Additional Diabetes Technology with the University of Pittsburgh
Details : Under the agreement, Genprex gains a worldwide, exclusive license to a patent application and related technology and a worldwide, non-exclusive license to use certain related know-how, all related to a gene therapy, GPX-002, for both Type 1 and Type 2 di...
Brand Name : GPX-002
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 18, 2023
Lead Product(s) : GPX-002
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Genprex
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : GPX-002
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Recipient : Genprex
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Genprex Signs Exclusive License to Additional Diabetes Technology with the University of Pittsburgh
Details : University of Pittsburgh grants Genprex a preclinical technology that transforms macrophages, complementary to the GPX-002 diabetes technology. Novel infusion process uses an endoscope and an AAV vector with a glucagon promoter to deliver the Pdx1 + MafA...
Brand Name : GPX-002
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 05, 2023
Lead Product(s) : GPX-002
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Recipient : Genprex
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : GPX-002
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Genprex
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Diabetic mice studies have shown that GPX-002, a gene therapy for diabetes, restored normal blood glucose levels for an extended period of time, which could translate to decades in humans.
Brand Name : GPX-002
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 15, 2022
Lead Product(s) : GPX-002
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Genprex
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Denileukin Diftitox,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Citius Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Preclinical research in a syngeneic solid tumor mouse model shows that I/ONTAK (E7777 or denileukin diftitox) enhances anti-tumor activity and significantly extends survival benefit of anti-PD-1 therapy.
Brand Name : I/ONTAK
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 22, 2022
Lead Product(s) : Denileukin Diftitox,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Citius Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : SNAP-CAR T Cell Therapy,Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Coeptis Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Current SNAP-CAR T therapies are designed to target specific tumor antigens that correspond to a specific cancer indication. This approach has proven effective in certain cancer types but limits the applicability of those CAR T therapies.
Brand Name : SNAP-CAR T Cell Therapy
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 21, 2022
Lead Product(s) : SNAP-CAR T Cell Therapy,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Coeptis Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : nanobody
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Low Doses of Inhalable 'nanobody' Fights Off Covid in Hamsters
Details : The treatment, dubbed PiN-21, could offer an affordable, needle-free option for treating early infections of SARS-CoV-2—the novel coronavirus behind COVID.
Brand Name : PiN-21
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
May 26, 2021
Lead Product(s) : nanobody
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AAV-based gene therapy
Therapeutic Area : Ophthalmology
Study Phase : Discovery
Sponsor : Astellas Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Cell Biology and Developmental Biology in University of Pittsburgh School of Medicine and Astellas will work jointly to evaluate and optimize the drug candidates with an aim to provide new treatment options to help recover and maintain vision in dry AMD ...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 24, 2020
Lead Product(s) : AAV-based gene therapy
Therapeutic Area : Ophthalmology
Highest Development Status : Discovery
Sponsor : Astellas Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Ab8
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The researchers reported in the journal Cell that Ab8 is highly effective in preventing and treating SARS-CoV-2 infection in mice and hamsters. In mice and hamsters, Ab8 proved effective in preventing and treating the disease; the journal Cell published ...
Brand Name : Ab8
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 14, 2020
Lead Product(s) : Ab8
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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