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Solutions","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"Allogeneic Umbilical Cord Mesenchymal Stem Cell","moa":"Stem cell proliferation","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Therapeutic Solutions","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Therapeutic Solutions \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Therapeutic Solutions \/ Inapplicable"},{"orgOrder":0,"company":"Therapeutic Solutions","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Pterostilbene","moa":"||NLRP3","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Therapeutic Solutions","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Therapeutic Solutions \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Therapeutic Solutions \/ Inapplicable"},{"orgOrder":0,"company":"Therapeutic Solutions","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Inapplicable","leadProduct":"Allogeneic Umbilical Cord Mesenchymal Stem Cell","moa":"Stem cell proliferation","graph1":"Neurology","graph2":"Preclinical","graph3":"Therapeutic Solutions","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Therapeutic Solutions \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Therapeutic Solutions \/ Inapplicable"}]

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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : FloraStilbene (mifepristone and pterostilbene) aims to stimulate the immune system in advanced breast cancer patients, with preclinical data showing efficacy in a triple-negative breast cancer model.

                          Product Name : FloraStilbene

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          March 01, 2024

                          Lead Product(s) : Mifepristone,Pterostilbene

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Lead Product(s) : Allogeneic Umbilical Cord Mesenchymal Stem Cell

                          Therapeutic Area : Neurology

                          Study Phase : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : JadiCell is a mesenchymal stem cell therapy having the ability to inhibit inflammasome activation and downstream chemical messengers of this inflammatory pathway, while concurrently stimulating regeneration of damaged neurons, being developed for Frontot...

                          Product Name : JadiCell

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 07, 2023

                          Lead Product(s) : Allogeneic Umbilical Cord Mesenchymal Stem Cell

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : FloraStilbene (RU486 and pterostilbene) to stimulate the immune system in advanced breast cancer patients. Preclinical data demonstrated that FloraStilbene overcame immune suppression induced in the 4T1 mouse model of triple negative breast cancer.

                          Product Name : FloraStilbene

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          October 20, 2023

                          Lead Product(s) : Mifepristone,Pterostilbene

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : JadiCell is a mesenchymal stem cell therapy led to preserving lung function and increasing repair cell production in mice with inflammation-induced lung injury in Acute Respiratory Distress Syndrome patients.

                          Product Name : JadiCell

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          June 26, 2023

                          Lead Product(s) : Allogeneic Umbilical Cord Mesenchymal Stem Cell

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : FloraStilbene™ to stimulate the immune system in advanced breast cancer patients. Preclinical data demonstrated that FloraStilbene overcame immune suppression induced in the 4T1 mouse model of triple negative breast cancer.

                          Product Name : FloraStilbene

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          June 03, 2023

                          Lead Product(s) : Mifepristone

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Under the collaboration, Cure Stat Rx will manufacture first in class breast cancer immunotherapy product FloraStilbene™ for a planned 12 patient Phase I/II trial aimed at assessing immunomodulatory activity of the drug candidate in advanced breast can...

                          Product Name : FloraStilbene

                          Product Type : Steroid

                          Upfront Cash : Undisclosed

                          May 15, 2023

                          Lead Product(s) : Mifepristone,Pterostilbene

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Cure Stat Rx

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : JadiCell is a mesenchymal stem cell therapy led to preserving lung function and increasing “repair cell” production in mice with inflammation-induced lung injury in COPD patients.

                          Product Name : JadiCell

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 20, 2023

                          Lead Product(s) : Allogeneic Umbilical Cord Mesenchymal Stem Cell

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : JadiCell is a mesenchymal stem cell therapy led to preserving lung function and increasing “repair cell” production in mice with inflammation-induced lung injury in COPD patients.

                          Product Name : JadiCell

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 13, 2023

                          Lead Product(s) : Allogeneic Umbilical Cord Mesenchymal Stem Cell

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Company is focused on treating the “living timebomb” condition of aortic aneurysms using stem cell derived exosomes as it suppress growth of aortic aneurysms.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 05, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : JadiCell (Mesenchymal Stem Cells) was shown to significantly improve survival in COVID-19 patients with Acute Respiratory Distress Syndrome (ARDS) and also reduce lung scarring associated with long-COVID-19.

                          Product Name : JadiCell

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 09, 2022

                          Lead Product(s) : Allogeneic Umbilical Cord Mesenchymal Stem Cell

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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