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Find Clinical Drug Pipeline Developments & Deals by Thryv Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : LQT-1213 (islasertib), a potent and selective serum glucocorticoid inducible kinase 1 inhibitor being investigated for the treatment of congenital Long QT Syndrome (cLQTS) Types 2 and 3.

                          Brand Name : LQT-1213

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 15, 2024

                          Lead Product(s) : Islasertib

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : LQT-1213 is a novel, first-in-class SGK1 inhibitor that the USFDA granted Orphan Drug Designation for the treatment of Long QT Syndrome.

                          Brand Name : LQT-1213

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 01, 2024

                          Lead Product(s) : Islasertib,Dofetilide

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The proceeds will be used to immediately accelerate Thryv's portfolio programs including, LQT-1213 (islasertib), a potent and selective inhibitor of Serum Glucocorticoid inducible Kinase (SGK1), being developed for the treatment of Long QT Syndrome and A...

                          Brand Name : LQT-1213

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 06, 2023

                          Lead Product(s) : Islasertib

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Investissement Québec

                          Deal Size : $5.0 million

                          Deal Type : Financing

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                          04

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Thryv’s Serum and Glucocorticoid Regulated Kinase-1 inhibitors significantly reduced the cardiac action potential duration in re-engineered heart cells derived from patients with the major forms of Congenital Long QT syndrome and in a model of Drug Ind...

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Not Applicable

                          November 02, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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