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    [{"orgOrder":0,"company":"Transgene","sponsor":"Merck Group","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"Tipapkinogen sovacivec","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Transgene \/ Merck KGaA","highestDevelopmentStatusID":"7","companyTruncated":"Transgene \/ Merck KGaA"},{"orgOrder":0,"company":"Transgene","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"Tipapkinogen sovacivec","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Transgene \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Transgene \/ Not Applicable"},{"orgOrder":0,"company":"Transgene","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"Tipapkinogen sovacivec","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"injection","sponsorNew":"Transgene \/ Merck","highestDevelopmentStatusID":"7","companyTruncated":"Transgene \/ Merck"},{"orgOrder":0,"company":"Transgene","sponsor":"Merck Group","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2021","type":"Not Applicable","leadProduct":"Tipapkinogen sovacivec","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Transgene \/ Merck KGaA","highestDevelopmentStatusID":"8","companyTruncated":"Transgene \/ Merck KGaA"},{"orgOrder":0,"company":"Transgene","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2022","type":"Not Applicable","leadProduct":"Avelumab","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Transgene \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Transgene \/ Not Applicable"},{"orgOrder":0,"company":"Transgene","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"Avelumab","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Transgene \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Transgene \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Tipapkinogen sovacivec

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                            01

                            Transgene

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                            CPhI India 2024
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                            Transgene

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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Transgene's Viral Cancer Vaccine Flunks Midphase Test

                            Details : TG4001 in combination with avelumab versus avelumab alone is being investigated in patients with recurrent or metastatic HPV16-positive cervical and anogenital tumors.

                            Brand Name : TG4001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 14, 2024

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Transgene

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                            CPhI India 2024
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                            Transgene

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                            CPhI India 2024
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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Transgene Announces Positive Interim Analysis Results of Phase II Trial Evaluating TG4001 + Avelumab vs Avelum...

                            Details : TG4001 is a therapeutic cancer vaccine candidate using an attenuated and modified poxvirus (MVA) as a vector expressing the HPV16 E6 and E7 proteins (rendered non-oncogenic) interleukin-2.

                            Brand Name : TG4001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 02, 2022

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Transgene

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                            CPhI India 2024
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                            Transgene

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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Merck Group

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Transgene Expands Phase II Trial of TG4001 in Combination With Avelumab Vs Avelumab Monotherapy in HPV16-posit...

                            Details : The initial Phase Ib/II trial conducted in Europe (France and Spain) has been amended to include a randomized comparison of the combination of TG4001 with avelumab versus avelumab monotherapy in anogenital cancers.

                            Brand Name : TG4001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 10, 2021

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Merck Group

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Transgene

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                            CPhI India 2024
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                            Transgene

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                            CPhI India 2024
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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Transgene Presents E-Poster Outlining Detailed Results from the Phase 1b/2 Trial of TG4001 in Combination With...

                            Details : Combination of TG4001 and avelumab demonstrated a clinically relevant anti-tumor activity with an overall response rate (ORR) of 23.5% .

                            Brand Name : TG4001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 09, 2020

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Transgene

                            France arrow
                            CPhI India 2024
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                            Transgene

                            France arrow
                            CPhI India 2024
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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Transgene Announces Detailed Results From Clinical Study of TG4001 in Combination With Avelumab in Advanced HP...

                            Details : Combination of TG4001 and avelumab demonstrates anti-tumor activity (23.5% overall response rate (ORR)) in patients with previously treated recurrent and/or metastatic HPV-related cancers.

                            Brand Name : TG4001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 27, 2020

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Transgene

                            France arrow
                            CPhI India 2024
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                            Transgene

                            France arrow
                            CPhI India 2024
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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Merck Group

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Transgene: Positive Clinical Results for TG4001 and TG6002 and Financial Visibility Secured Until 2022

                            Details : The analysis of the efficacy data from the Phase 1b/2 trial combining TG4001 with avelumab in HPV16-positive recurrent and/or metastatic malignancies showed a promising clinical activity in the overall study population.

                            Brand Name : TG4001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            September 16, 2020

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Merck Group

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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