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Find Clinical Drug Pipeline Developments & Deals for Tipapkinogen sovacivec

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                          01

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : TG4001 in combination with avelumab versus avelumab alone is being investigated in patients with recurrent or metastatic HPV16-positive cervical and anogenital tumors.

                          Product Name : TG4001

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 14, 2024

                          Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : TG4001 is a therapeutic cancer vaccine candidate using an attenuated and modified poxvirus (MVA) as a vector expressing the HPV16 E6 and E7 proteins (rendered non-oncogenic) interleukin-2.

                          Product Name : TG4001

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 11, 2022

                          Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The initial Phase Ib/II trial conducted in Europe (France and Spain) has been amended to include a randomized comparison of the combination of TG4001 with avelumab versus avelumab monotherapy in anogenital cancers.

                          Product Name : TG4001

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 03, 2021

                          Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Merck Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Combination of TG4001 and avelumab demonstrates anti-tumor activity (23.5% overall response rate (ORR)) in patients with previously treated recurrent and/or metastatic HPV-related cancers.

                          Product Name : TG4001

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 27, 2020

                          Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The analysis of the efficacy data from the Phase 1b/2 trial combining TG4001 with avelumab in HPV16-positive recurrent and/or metastatic malignancies showed a promising clinical activity in the overall study population.

                          Product Name : TG4001

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 16, 2020

                          Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Merck Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Combination of TG4001 and avelumab demonstrated a clinically relevant anti-tumor activity with an overall response rate (ORR) of 23.5% .

                          Product Name : TG4001

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 11, 2020

                          Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Merck & Co

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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