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Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Hutchmed \/ Inapplicable"},{"orgOrder":0,"company":"Duality Biologics","sponsor":"BeiGene","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody-drug Conjugate","year":"2025","type":"Licensing Agreement","leadProduct":"BG-C9074","moa":"||B7-H4","graph1":"Oncology","graph2":"Phase I","graph3":"Duality Biologics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Duality Biologics \/ BeiGene","highestDevelopmentStatusID":"6","companyTruncated":"Duality Biologics \/ BeiGene"}]

Find Clinical Drug Pipeline Developments & Deals for Tislelizumab

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Bria-OTS is a personalized off-the-shelf next-gen immunotherapy, which is being evaluated as monotherapy and in combination Tislelizumab and cyclophosphamide for advanced metastatic breast cancer.

                          Product Name : Bria-OTS

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          February 03, 2025

                          Lead Product(s) : Bria-OTS,Tislelizumab,Cyclophosphamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Under the agreement, combining BeiGene's Tevimbra (tislelizumab), a PD-1 checkpoint inhibitor, and ImmunityBio's Anktiva, to conduct a confirmatory randomized Phase 3 clinical trial for S-IV NSCLC.

                          Product Name : Tevimbra

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          January 29, 2025

                          Lead Product(s) : Tislelizumab,Nogapendekin Alfa Inbakicept,Docetaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : BeiGene

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Under the terms of the agreement, MAIA will sponsor and fund the planned clinical trials of THIO-102 and BeiGene will provide Tislelizumab for hepatocellular carcinoma, SCLC, and CRC.

                          Product Name : THIO-102

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 07, 2025

                          Lead Product(s) : THIO-102,Tislelizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : BeiGene

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : BeiGene has exercised its exclusive option to acquire global development, manufacturing, and commercialization rights for an ADC, BG-C9074 (DB-1312) from DualityBio.

                          Product Name : DB-1312

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          January 03, 2025

                          Lead Product(s) : BG-C9074,Tislelizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : BeiGene

                          Deal Size : $1,300.0 million

                          Deal Type : Licensing Agreement

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                          05

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 31, 2024

                          Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                          Product Name : Tevimbra

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 27, 2024

                          Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Bria-OTS is a personalized off-the-shelf next-gen immunotherapy, which is being evaluated as monotherapy and in combination Tislelizumab and cyclophosphamide for advanced metastatic breast cancer.

                          Product Name : Bria-OTS

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 21, 2024

                          Lead Product(s) : Bria-OTS,Tislelizumab,Cyclophosphamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The collaboration aims to advance human clinical evaluation of the combination of BeiGene's anti-PD-1 antibody, Tevimbra (tislelizumab), with Indaptus’ Decoy20, a novel treatment for cancer.

                          Product Name : Decoy20

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 22, 2024

                          Lead Product(s) : Decoy20,Tislelizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : BeiGene

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          09

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                          Product Name : Tevimbra

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 21, 2024

                          Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The collaboration will evaluate the combination of Anbogen's HDAC inhibitor, ABT-301, with BeiGene's anti-PD-1 antibody Tevimbra (tislelizumab), in pMMR or MSS metastatic colorectal cancer.

                          Product Name : ABT-301

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 27, 2024

                          Lead Product(s) : ABT-301,Tislelizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : BeiGene

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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