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    [{"orgOrder":0,"company":"Seagen","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Tisotumab Vedotin","moa":"Microtubule protein","graph1":"Oncology","graph2":"Phase II","graph3":"Seagen","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravitreous","sponsorNew":"Seagen \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Seagen \/ Not Applicable"},{"orgOrder":0,"company":"Genmab","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"DENMARK","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Tisotumab Vedotin","moa":"Microtubule 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II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Pfizer Inc \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Pfizer Inc \/ Not Applicable"}]

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    Tisotumab Vedotin

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                            01

                            Pfizer Inc

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                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab,Carboplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Tisotumab Vedotin Phase 2 Shows Antitumor Activity in Recurrent Head and Neck Cancer

                            Details : Tivdak (tisotumab vedotin) is an ADC that acts as coagulation factor III binding agent & tubulin inhibitor. It is being evaluated for the treatment of Head and Neck Squamous Cell Carcinoma.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 03, 2024

                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab,Carboplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Pfizer Inc

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                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Genmab

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            FDA Grants Full Approval for TIVDAK® to Treat Recurrent or Metastatic Cervical Cancer

                            Details : Tivdak (tisotumab vedotin) is an antibody-drug conjugate that acts as coagulation factor III binding agent & tubulin inhibitor. It is approved for recurrent or metastatic cervical cancer.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 29, 2024

                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Genmab

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Pfizer Inc

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                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Alvotech Announces Positive Results for AVT03, a Proposed Biosimilar for Prolia and Xgeva

                            Details : Tivdak (tisotumab vedotin-tftv) is an antibody-drug conjugate that acts as coagulation factor III binding agent. It is being evaluated for the treatment of recurrent or metastatic cervical cancer.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 09, 2024

                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            EMA Validates Tisotumab Vedotin Application for Recurrent or Metastatic Cervical Cancer

                            Details : Tivdak (tisotumab vedotin-tftv) is a tissue factor (TF)-directed antibody drug conjugate. It is approved by USFDA for the treatment of cervical cancer.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 02, 2024

                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            TIVDAK® BLA Accepted for Priority Review in Cervical Cancer Patients

                            Details : Tivdak (tisotumab vedotin-tftv) is an ADC composed of Genmab’s antibody targeting tissue factor and Pfizer’s technology, currently evaluated in phase 3 for recurrent cervical cancer.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 09, 2024

                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            TIVDAK® (tisotumab vedotin-tftv) Significantly Prolonged Overall Survival in Patients with Recurrent or Metas...

                            Details : Tivdak (tisotumab vedotin) is an antibody-drug conjugate, which is investigating in phase III and met its primary endpoint of overall survival for recurrent or metastatic cervical cancer compared to chemotherapy.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 22, 2023

                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Genmab

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                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Genmab and Seagen Announce that TIVDAK® (tisotumab vedotin-tftv) Met its Primary Endpoint of Improved Overall...

                            Details : TIVDAK (tisotumab vedotin) is an antibody-drug conjugate, which is investigating in phase III and met its primary endpoint of overall survival for recurrent or metastatic cervical cancer compared to chemotherapy.

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 04, 2023

                            Lead Product(s) : Tisotumab Vedotin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Genmab

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                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Genmab and Seagen Present Data from Tisotumab Vedotin (TIVDAK®) Clinical Development Program and Additional C...

                            Details : Interim results of tisotumab vedotin (Tivdak) plus pembrolizumab from Phase 1b/2 innovaTV 205 trial, showing 41% objective response rate in first-line patients with recurrent or metastatic cervical cancer (r/mCC).

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 06, 2022

                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Genmab Announces Multiple Abstracts to be Presented at the 2022 American Society of Clinical Oncology (ASCO) A...

                            Details : Tisotumab vedotin-tftv (TIVDAK®) is an antibody-drug conjugate (ADC) composed of Genmab’s human monoclonal antibody directed to tissue factor and Seagen’s ADC technology that utilizes protease-cleavable linker that covalently attaches MMAE to antibo...

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 26, 2022

                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Genmab

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                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab,Carboplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Genmab and Seagen Present First Data on Tisotumab Vedotin (TIVDAK®) in Patients with Head and Neck Squamous C...

                            Details : Data from innovaTV 207 phase 2 trial of TIVDAK (tisotumab vedotin), an antibody-drug conjugate, demonstrated manageable safety profile and promising preliminary antitumor activity, also met primary endpoint of confirmed ORR per investigator, achieved by ...

                            Brand Name : Tivdak

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 24, 2022

                            Lead Product(s) : Tisotumab Vedotin,Pembrolizumab,Carboplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Seagen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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