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Find Clinical Drug Pipeline Developments & Deals by Tiziana Life Sciences

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                          Top Deals by Deal Size (USD bn)

                          01

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The significant grant will fund a key research study over the next several years, advancing clinical studies of TZLS-401 (foralumab), anti-CD3 as a potential treatment for Alzheimer’s disease.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 19, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : National Institutes of Health

                          Deal Size : $4.0 million

                          Deal Type : Funding

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                          02

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody (mAb), it is under phase 2 clinical development for the treatment of non-active secondary progressive Multiple Sclerosis.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 24, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb that is being evaluated in patients with moderate Alzheimer’s disease.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 26, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody (mAb), it is under phase 2 clinical development for the treatment of non-active secondary progressive Multiple Sclerosis.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 11, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody (mAb), it is under phase 2 clinical development for the treatment of non-active secondary progressive Multiple Sclerosis.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 04, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb and has demonstrated a favorable safety profile and clinical response in patients with Non-ASPMS.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 13, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody under phase 2 clinical development for multiple sclerosis treatment.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 23, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb and has demonstrated a favorable safety profile and clinical response in patients with Non-ASPMS.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 22, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TZLS-401 (foralumab) is a fully human anti-CD3 monoclonal antibody dampening inflammation, under phase 2 development for multiple sclerosis.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 08, 2024

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens inflammation by modulating T cell function. It is under phase 2 clinical development for the treatment of Multiple Sclerosis.

                          Brand Name : TZLS-401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 19, 2023

                          Lead Product(s) : Foralumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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