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Find Clinical Drug Pipeline Developments & Deals for TNG908

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The proceeds are expected to enable rapid expansion across multiple tumor types for the TNG908 and TNG462 PRMT5 programs, as well as maintain funding through proof-of-concept for each of its clinical-stage programs as the Company awaits clinical data.

                          Brand Name : TNG908

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 10, 2023

                          Lead Product(s) : TNG908

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Nextech

                          Deal Size : $80.0 million

                          Deal Type : Private Placement

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : TNG908 is administered orally, a selective PRMT5 inhibitor that drives tumor regression, it is being developed for the treament of MTAP-deleted glioblastoma (GBM).

                          Brand Name : TNG908

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 14, 2023

                          Lead Product(s) : TNG908

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : TNG908 is an investigational PRMT5 inhibitor with a novel MTA-cooperative binding mechanism designed to leverage the synthetic lethal interaction between PRMT5 inhibition and MTAP deletion.

                          Brand Name : TNG908

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 19, 2022

                          Lead Product(s) : TNG908

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : TNG908, is a potent, synthetic lethal inhibitor of PRMT5 that works selectively in cells with MTAP deletion drives tumor regressions in MTAP-deleted xenograft models across multiple histologies.

                          Brand Name : TNG908

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 08, 2022

                          Lead Product(s) : TNG908

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : TNG908, a potent, synthetic lethal inhibitor of protein arginine methyl transferase 5 inhibitor that selectively kills cancer cells with methylthioadenosine phosphorylase deletions, while sparing normal cells.

                          Brand Name : TNG908

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 03, 2022

                          Lead Product(s) : TNG908

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The proceeds are expected to provide Tango with the capital needed to further develop its pipeline, including ND filing for Tango’s lead program, TNG908; IND filing for its USP1 inhibitor; ND filing for an undisclosed target and Progressing multiple pr...

                          Brand Name : TNG908

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 14, 2021

                          Lead Product(s) : TNG908

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : BCTG Acquisition Corp

                          Deal Size : $353.0 million

                          Deal Type : Acquisition

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