Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Nextech
Deal Size : $80.0 million
Deal Type : Private Placement
Tango Therapeutics Announces $80 Million Private Placement Financing
Details : The proceeds are expected to enable rapid expansion across multiple tumor types for the TNG908 and TNG462 PRMT5 programs, as well as maintain funding through proof-of-concept for each of its clinical-stage programs as the Company awaits clinical data.
Brand Name : TNG908
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 10, 2023
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Nextech
Deal Size : $80.0 million
Deal Type : Private Placement
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TNG908 is administered orally, a selective PRMT5 inhibitor that drives tumor regression, it is being developed for the treament of MTAP-deleted glioblastoma (GBM).
Brand Name : TNG908
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 14, 2023
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TNG908 is an investigational PRMT5 inhibitor with a novel MTA-cooperative binding mechanism designed to leverage the synthetic lethal interaction between PRMT5 inhibition and MTAP deletion.
Brand Name : TNG908
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 19, 2022
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TNG908, is a potent, synthetic lethal inhibitor of PRMT5 that works selectively in cells with MTAP deletion drives tumor regressions in MTAP-deleted xenograft models across multiple histologies.
Brand Name : TNG908
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TNG908, a potent, synthetic lethal inhibitor of protein arginine methyl transferase 5 inhibitor that selectively kills cancer cells with methylthioadenosine phosphorylase deletions, while sparing normal cells.
Brand Name : TNG908
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 03, 2022
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : BCTG Acquisition Corp
Deal Size : $353.0 million
Deal Type : Acquisition
Tango Therapeutics and BCTG Acquisition Corp. Announce Merger Agreement
Details : The proceeds are expected to provide Tango with the capital needed to further develop its pipeline, including ND filing for Tango’s lead program, TNG908; IND filing for its USP1 inhibitor; ND filing for an undisclosed target and Progressing multiple pr...
Brand Name : TNG908
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 14, 2021
Lead Product(s) : TNG908
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : BCTG Acquisition Corp
Deal Size : $353.0 million
Deal Type : Acquisition
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