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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : TRX103, a first-in-class Type 1 Treg cell therapy candidate, which is being evaluated for the treatment of patients with treatment-refractory crohn’s disease.

                          Brand Name : TRX103

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 07, 2024

                          Lead Product(s) : TRX103

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : TRX103, a first-in-class Type 1 Treg cell therapy, is specifically designed for patients with autoimmune and inflammatory disorders, including those undergoing HSCT.

                          Brand Name : TRX103

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 10, 2024

                          Lead Product(s) : TRX103

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The net proceeds will be used to bring universal allogeneic regulatory T (Treg), including TRX103 and CAR-Treg cell therapies, TRX301, for autoimmune and inflammatory diseases.

                          Brand Name : TRX103

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 17, 2024

                          Lead Product(s) : TRX103

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : The Column Group

                          Deal Size : $75.0 million

                          Deal Type : Series A Financing

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