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    [{"orgOrder":0,"company":"Tr1X Bio","sponsor":"California Institute for Regenerative Medicine","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Funding","leadProduct":"TRX103","moa":"Treg cell","graph1":"Immunology","graph2":"Phase I","graph3":"Tr1X Bio","amount2":0.01,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0.01,"dosageForm":"Intravenous Infusion","sponsorNew":"Tr1X Bio \/ California Institute for Regenerative Medicine","highestDevelopmentStatusID":"6","companyTruncated":"Tr1X Bio \/ California Institute for Regenerative Medicine"},{"orgOrder":0,"company":"Tr1X Bio","sponsor":"The Column Group","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Series A Financing","leadProduct":"TRX103","moa":"Undisclosed","graph1":"Immunology","graph2":"Phase I","graph3":"Tr1X Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tr1X Bio \/ The Column Group","highestDevelopmentStatusID":"6","companyTruncated":"Tr1X Bio \/ The Column Group"},{"orgOrder":0,"company":"Tr1X Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"TRX103","moa":"Undisclosed","graph1":"Immunology","graph2":"Phase I","graph3":"Tr1X Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tr1X Bio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Tr1X Bio \/ Inapplicable"},{"orgOrder":0,"company":"Tr1X Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"TRX103","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"IND Enabling","graph3":"Tr1X Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tr1X Bio \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Tr1X Bio \/ Inapplicable"}]

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                            01

                            Tr1X Bio

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                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : California Institute for Regenerative Medicine

                            Deal Size : $8.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Tr1x Awarded $8 Million Cirm Grant for TRX103 Phase 1/2a Clinical Trial

                            Details : The funding aims to advance the development of TRX103 an engineered Tr1 Treg cell therapy for use in the prevention of GvHD in blood cancer patients undergoing mismatched stem cell transplants.

                            Product Name : TRX103

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            April 04, 2025

                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : California Institute for Regenerative Medicine

                            Deal Size : $8.0 million

                            Deal Type : Funding

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                            02

                            Tr1X Bio

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                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Tr1X Doses First Patient in GvHD Trial with TRX103, a Type 1 Treg Cell Therapy

                            Details : TRX103, a first-in-class Type 1 Treg cell therapy, is specifically designed for patients with autoimmune and inflammatory disorders, including those undergoing HSCT.

                            Product Name : TRX103

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            October 07, 2024

                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : TRX103

                            Therapeutic Area : Gastroenterology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tr1X Announces FDA Clearance of IND Application for TRX103 for Refractory Crohn’s Disease

                            Details : TRX103, a first-in-class Type 1 Treg cell therapy candidate, which is being evaluated for the treatment of patients with treatment-refractory crohn’s disease.

                            Product Name : TRX103

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            July 08, 2024

                            Lead Product(s) : TRX103

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

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                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : The Column Group

                            Deal Size : $75.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Tr1X Raises $75M for Universal CAR-Treg Therapies Development

                            Details : The net proceeds will be used to bring universal allogeneic regulatory T (Treg), including TRX103 and CAR-Treg cell therapies, TRX301, for autoimmune and inflammatory diseases.

                            Product Name : TRX103

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 17, 2024

                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : The Column Group

                            Deal Size : $75.0 million

                            Deal Type : Series A Financing

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