Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Vanda Seeks FDA Hearing for Tradipitant Gastroparesis NDA
Details : VLY-686 (tradipitant) is an NK1R Inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of gastroparesis via oral capsule.
Product Name : VLY-686
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 27, 2025
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Declines to Approve Vanda's Marketing Application for Tradipitant in Gastroparesis
Details : VLY-686 (tradipitant) is an NK1R Inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of gastroparesis via oral capsule.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
September 19, 2024
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Eli Lilly
Deal Size : Not Applicable
Deal Type : Not Applicable
Vanda Pharmaceuticals Reports Positive Phase III Result for Tradipitant in Motion Sickness
Details : VLY-686 (tradipitant) is a neurokinin-1 receptor antagonist licensed from Eli Lilly. Tradipitant is currently in clinical development for gastroparesis and motion sickness.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
May 15, 2024
Lead Product(s) : Tradipitant
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Eli Lilly
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VLY-686 (tradipitant) is an NK1R Inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of gastroparesis via oral capsule.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
December 05, 2023
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Vanda Pharmaceuticals Reports Results from a Phase III study of Tradipitant in Motion Sickness
Details : VLY-686 (tradipitant) is a neurokinin-1 receptor antagonist licensed by Vanda from Eli Lilly and Company. Tradipitant is currently in clinical development for gastroparesis and motion sickness.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
May 25, 2023
Lead Product(s) : Tradipitant
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Vanda Pharmaceuticals Announces Presentations at DDW 2022
Details : Tradipitant (VLY-686 or LY686017) is an experimental drug that is a neurokinin 1 antagonist. It works by blocking substance P, a small signaling molecule.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
May 19, 2022
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Vanda Pharmaceuticals Reports Results from the Phase III Study of Tradipitant in Gastroparesis
Details : Tradipitant is a neurokinin-1 receptor antagonist licensed by Vanda from Eli Lilly and Company. Tradipitant is currently in clinical development for gastroparesis and motion sickness.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
February 04, 2022
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The study was designed to determine whether tradipitant plus standard of care is superior to placebo plus standard of care in treating hospitalized patients with COVID-19 pneumonia who required supplemental oxygen support.
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
August 03, 2021
Lead Product(s) : Tradipitant
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Vanda Pharmaceuticals Provides Update on Tradipitant Development Program
Details : Article describes Vanda's Phase II double-blind trial of 152 adults with gastroparesis in the U.S. Patients receiving tradipitant had a significant decrease in nausea score at week 4 compared with placebo, and a significant increase in of nausea-free day...
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
August 31, 2020
Lead Product(s) : Tradipitant
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tradipitant
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Interim analysis of the ODYSSEY study showed that a 14 day tradipitant treatment accelerated clinical improvement by day 7 (HR=2.55, p=0.0375).
Product Name : VLY-686
Product Type : Small molecule
Upfront Cash : Not Applicable
August 18, 2020
Lead Product(s) : Tradipitant
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable