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Securities","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"ONP-002","moa":"","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase I","graph3":"Oragenics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"","sponsorNew":"Oragenics \/ Dawson James Securities","highestDevelopmentStatusID":"6","companyTruncated":"Oragenics \/ Dawson James Securities"},{"orgOrder":0,"company":"Oragenics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"ONP-002","moa":"","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase I","graph3":"Oragenics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"","sponsorNew":"Oragenics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Oragenics \/ Not Applicable"}]

Find Clinical Drug Pipelines for Trauma (Emergency, Injury, Surgery)

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Protein-based Crosslinked Hydrogel

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Study Phase : Preclinical

                          Sponsor : Kalinga Institute of Technology

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Details : Through the agreement, Supriya Lifescience will focus on the advancement of GelHeal, a protein-based crosslinked Hydrogel, gel-based cream, which is being evaluated for the treatment of deep wounds.

                          Brand Name : GelHeal

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 06, 2023

                          Lead Product(s) : Protein-based Crosslinked Hydrogel

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : Kalinga Institute of Technology

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Supriya

                          02

                          Lead Product(s) : Sodium Hyaluronate

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Study Phase : Approved

                          Sponsor : Lumenis

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : M22 medical wound dressing (sodium hyaluronate) is a versatile laser treatment system based on Lumenis' medical beauty concept of "30% Laser Treatment and 70% Postoperative care.

                          Brand Name : M22 Medical Wound Dressing

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 10, 2023

                          Lead Product(s) : Sodium Hyaluronate

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Approved

                          Sponsor : Lumenis

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Bloomage Company Banner

                          03

                          Details : Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments, as well as manufacturing a laboratory-scale batch of IHL-216A (Cannabidiol) to support toxicolog...

                          Brand Name : IHL-216A

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 22, 2021

                          Lead Product(s) : Cannabidiol,Isoflurane

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : Incannex Healthcare

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Skyepharma Company Banner

                          04

                          Details : Elezanumab is a monoclonal antibody of the human immunoglobulin (Ig)G1 isotype that binds selectively to repulsive guidance molecule A (RGMa). Elezanumab is being investigated to treat spinal cord injuries, multiple sclerosis and acute ischemic stroke.

                          Brand Name : ABT-555

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 28, 2020

                          Lead Product(s) : Elezanumab

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Abbvie Company Banner

                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The proceeds will be used for the development of company's lead therapeutic, MIIST305, an orally delivered, shelf-stable, gut-restricted therapy, as a prophylactic radiation countermeasure.

                          Brand Name : MIIST305

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 31, 2024

                          Lead Product(s) : MIIST305

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : JWMRP

                          Deal Size : $2.2 million

                          Deal Type : Funding

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                          06

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Under the partnership, PT Ferron Par Pharmaceuticals will become Moleac's exclusive partner in Indonesia of NeuroAiD II MLC901 which consists of extracts from 9 herbal components.

                          Brand Name : NeuroAiD II

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 21, 2024

                          Lead Product(s) : MLC901

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Approved

                          Sponsor : PT Ferron Par Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          07

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The contract aims to develop Synedgen’s lead therapeutic, MIIST305, an oral, glycocalyx-targeted therapy, to address GI-ARS arising from acute exposure to ionizing radiation.

                          Brand Name : MIIST305

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 15, 2024

                          Lead Product(s) : MIIST305

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : BARDA

                          Deal Size : $119.0 million

                          Deal Type : Agreement

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                          08

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : ONP-002 is a new chemical entity (NCE) designed to target the brain through delivery into the nasal cavity and onward to the brain.

                          Brand Name : ONP-002

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 08, 2024

                          Lead Product(s) : ONP-002

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The company will use the proceeds to fund the development of the product candidates in its pipeline, including

                          Brand Name : V005

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 04, 2024

                          Lead Product(s) : Human Acellular Vessel

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : EF Hutton LLC

                          Deal Size : $30.0 million

                          Deal Type : Public Offering

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                          10

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : ExoPTEN comprises exosomes loaded with siRNA that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for the treatment of acute spinal cord injury.

                          Brand Name : ExoPTEN

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 06, 2024

                          Lead Product(s) : ExoPTEN

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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