Lead Product(s) : Bucillamine
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Attwill Medical Solutions
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims for the clinical and commercial development of Revive’s lyophilized formulation of Bucillamine, a potent antioxidant and anti-inflammatory and may be helpful for orphan indications in rare inflammatory disorders such as ischemia-...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 18, 2023
Lead Product(s) : Bucillamine
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Attwill Medical Solutions
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : OWL-1410
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Owl Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, Owl Therapeutics will advance Abliva's clinical development of NeuroSTAT (OWL-1410) with orphan drug designation, which is under development for the prevention and treatment of moderate to severe traumatic brain injury (TBI).
Brand Name : NeuroSTAT
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 17, 2023
Lead Product(s) : OWL-1410
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Owl Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Exosome
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI), yielding neuron regeneration and rewiring in traumatically damaged spinal cord.
Brand Name : ExoPTEN
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 13, 2023
Lead Product(s) : Exosome
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AAV-Based Gene Therapy
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Stand Up Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : STUP-001 (AAV-based gene therapy), the innovative GT medication, unties the knot for spinal cord injured patient through motor sensory neuron reprogramming technology. Cell fate conversion using virus transduction system is of great interest in the field...
Brand Name : STUP-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 29, 2022
Lead Product(s) : AAV-Based Gene Therapy
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Stand Up Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : TT-20
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Perceptive Xontogeny Venture Fund
Deal Size : $35.0 million
Deal Type : Series A Financing
Tellus Therapeutics Announces $35 Million Series A Financing
Details : Tellus’s lead candidate, TT-20, is derived from a class of molecules found in breast milk, which promote the generation of myelin from postnatal neural stem populations.
Brand Name : TT-20
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 13, 2022
Lead Product(s) : TT-20
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Perceptive Xontogeny Venture Fund
Deal Size : $35.0 million
Deal Type : Series A Financing
Lead Product(s) : Human Amniotic Fluid
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Dermacyte® Amniotic Wound Care Liquid (human amniotic fluid), a cell-free amniotic injection that is being developed under Merakris’ investigational New Drug (IND) approval for would healing.
Brand Name : Dermacyte Liquid
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 29, 2022
Lead Product(s) : Human Amniotic Fluid
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : LUT017
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : California Institute of Regenerative Medicine
Deal Size : $5.0 million
Deal Type : Funding
Details : The award will allow for the completion of Investigational New Drug enabling studies. Specifically, the funds will be utilized for the manufacturing of LUT017 active pharmaceutical ingredient and the final formulated drug product (LUT017 gel) to supply t...
Brand Name : LUT017
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 24, 2022
Lead Product(s) : LUT017
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : California Institute of Regenerative Medicine
Deal Size : $5.0 million
Deal Type : Funding
Lead Product(s) : ECP-101
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ECP-101, unique drug therapy involving cannabinoids and psychedelics will be used to promote a quick recovery and overcome the long term consequences often seen with mTBI.
Brand Name : ECP-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 07, 2022
Lead Product(s) : ECP-101
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ECP-101
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ECP Pharma Developing Innovative Drug Products For Neurological and Central Nervous System Diseases
Details : ECP-101, unique drug therapy involving cannabinoids and psychedelics will be used to promote a quick recovery and overcome the long term consequences often seen with mTBI.
Brand Name : ECP-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 22, 2022
Lead Product(s) : ECP-101
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Psilocybine,Cannabidiol
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Wesana Health Announces Positive Feedback From Pre-IND Meeting With FDA on SANA-013
Details : The Company received positive written responses from the FDA, outlining the requirements to open the IND and commence with clinical studies for SANA-013,for the treatment of Traumatic Brain Injury (TBI) related major depressive disorder.
Brand Name : SANA-013
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 14, 2022
Lead Product(s) : Psilocybine,Cannabidiol
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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