Lead Product(s) : Entolimod
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Tivic Health Systems
Deal Size : $1.5 million
Deal Type : Licensing Agreement
Tivic Health Gains Global Rights to Phase III TLR5 Agonist from Statera
Details : Under the licensing agreement, Tivic Health acquired worldwide exclusive rights of STAT-600 (entolimod), toll-like Receptor 5 (TLR5) agonist for the treatment of acute radiation syndrome.
Product Name : STAT-600
Product Type : Peptide
Upfront Cash : $1.5 million
February 12, 2025
Lead Product(s) : Entolimod
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Tivic Health Systems
Deal Size : $1.5 million
Deal Type : Licensing Agreement
Lead Product(s) : Bromelain
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
MediWound Announces Fda Has Accepted for Review Supplement To NexoBrid Bla
Details : NexoBrid (anacaulase-bcdb) is a topically administered biological product for enzymatically removing nonviable burn tissue, being studied in phase 3 trials for partial and full-thickness burns.
Product Name : NexoBrid
Product Type : Enzyme
Upfront Cash : Inapplicable
September 01, 2024
Lead Product(s) : Bromelain
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Human Acellular Vessel (HAV) in establishing vascular access and plans to file a Biologics License Application (BLA) for the treatment of vascular trauma with the Food and Drug Administration (FDA) during the 4th quarter of 2023.
Product Name : Humacyl
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
December 09, 2023
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Oberland Capital Management
Deal Size : $160.0 million
Deal Type : Financing
Humacyte and Oberland Capital Announce Funding Arrangement Totaling Up to $160 Million
Details : The financing will be used to support planned development and commercialization of Humacyte’s Human Acellular Vessel™ (HAV™) for use in urgent arterial repair following extremity vascular trauma and earlier-stage product candidates.
Product Name : Humacyl
Product Type : Cell and Gene therapy
Upfront Cash : $40.0 million
December 05, 2023
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Oberland Capital Management
Deal Size : $160.0 million
Deal Type : Financing
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Human Acellular Vessel (HAV) is the off-the-shelf bioengineered human artery that has been observed to repopulate with the patient’s own cells to provide a durable, infection-resistant replacement for damaged and diseased arteries.
Product Name : Humacyl
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
November 09, 2023
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bromelain
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : BARDA
Deal Size : $175.0 million
Deal Type : Funding
MediWound Announces an Additional $10 Million Award from BARDA
Details : The supplemental funding will support replenishment of NexoBrid (Anacaulase-bcdb) previously procured for emergency preparedness, the pediatric indication sBLA submission to the U.S.FDA, and enrollment of an additional 50 patients in ongoing expanded acc...
Product Name : NexoBrid
Product Type : Enzyme
Upfront Cash : Undisclosed
September 05, 2023
Lead Product(s) : Bromelain
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : BARDA
Deal Size : $175.0 million
Deal Type : Funding
Lead Product(s) : Ronopterin
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VAS203 (ronopterin) significantly reduces lactate levels in brain microdialysate from TBI patients reflecting energetic stability and neuroprotection during the early vulnerable phase.
Product Name : VAS203
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 07, 2022
Lead Product(s) : Ronopterin
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Human Acellular Vessels (HAV) are investigational engineered off-the-shelf replacement vessels initially being developed for vascular repair, reconstruction and replacement.
Product Name : Humacyl
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
September 09, 2022
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ALM-488
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALM-488 is a proprietary fluorescent peptide-dye conjugate in the visible spectrum and can be visualized with fluorescently enabled instrumentation including filter modified loupe systems, portable handheld systems, microscopes and laparoscopes.
Product Name : ALM-488
Product Type : Peptide
Upfront Cash : Inapplicable
August 23, 2022
Lead Product(s) : ALM-488
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Human Acellular Vessels (HAV) are investigational engineered off-the-shelf replacement vessels initially being developed for vascular repair, reconstruction and replacement.
Product Name : Humacyl
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
July 07, 2022
Lead Product(s) : Human Acellular Vessel
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable