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Find Clinical Drug Pipeline Developments & Deals for TRV027

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                          01

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : TRV027 is a novel AT1 receptor selective agonist that specifically binds to and rebalances AT1 receptor activation within the RAAS, blocking the damaging pathway that leads to acute lung damage and abnormal blood clotting.

                          Product Name : TRV027

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          July 26, 2021

                          Lead Product(s) : TRV027

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : TRV027, the Company’s novel AT1 receptor selective agonist, represents a new approach to targeting the AT1 receptor and reversing organ damage caused by RAAS imbalance, has been selected for an NIH ACTIV trial in COVID-19 patients.

                          Product Name : TRV027

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          June 05, 2021

                          Lead Product(s) : TRV027

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : National Institutes of Health

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Live presentation highlighting TRV027 as a potential treatment for COVID-19 acute respiratory distress syndrome (ARDS) / abnormal clotting.

                          Product Name : TRV027

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          September 21, 2020

                          Lead Product(s) : TRV027

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Through an ongoing collaboration with ICL, the Company is evaluating the potential of TRV027 to treat acute lung damage / abnormal blood clotting associated with COVID-19.

                          Product Name : TRV027

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          August 24, 2020

                          Lead Product(s) : TRV027

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Imperial College London

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          British Heart Foundation

                          Country arrow
                          Interphex
                          Not Confirmed

                          British Heart Foundation

                          Country arrow
                          Interphex
                          Not Confirmed

                          Details : A molecule known as TRV027, could put a brake on many of the dangerous processes which occur in Covid-19, such as lung damage and blood clots. The cell pathways targeted by the drug are thought to be major drivers of severe illness in Covid-19.

                          Product Name : TRV027

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          June 15, 2020

                          Lead Product(s) : TRV027

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Imperial College London

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Collaboration to evaluate the potential of TRV027, a novel AT1 receptor selective agonist, to treat acute lung injury contributing to acute respiratory distress syndrome (ARDS) in COVID-19 patients.

                          Product Name : TRV027

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          February 06, 2020

                          Lead Product(s) : TRV027

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase I

                          Sponsor : Trevena

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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