[{"orgOrder":0,"company":"TTC Oncology","sponsor":"University of Illinois Chicago","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"TTC-352","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"TTC Oncology","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"TTC Oncology \/ University of Illinois Chicago","highestDevelopmentStatusID":"6","companyTruncated":"TTC Oncology \/ University of Illinois Chicago"},{"orgOrder":0,"company":"TTC Oncology","sponsor":"University of Illinois","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Funding","leadProduct":"TTC-352","moa":"Selective estrogen receptor","graph1":"Oncology","graph2":"Phase I","graph3":"TTC Oncology","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"TTC Oncology \/ University of Illinois","highestDevelopmentStatusID":"6","companyTruncated":"TTC Oncology \/ University of Illinois"},{"orgOrder":0,"company":"TTC Oncology","sponsor":"Lantern Pharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"TTC-352","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"TTC Oncology","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"TTC Oncology \/ Lantern Pharma","highestDevelopmentStatusID":"6","companyTruncated":"TTC Oncology \/ Lantern Pharma"},{"orgOrder":0,"company":"Lantern Pharma","sponsor":"TTC Oncology","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"TTC-352","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Lantern Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Lantern Pharma \/ TTC Oncology","highestDevelopmentStatusID":"6","companyTruncated":"Lantern Pharma \/ TTC Oncology"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Lantern Pharma is receiving an exclusive right to license TTC-352, an orally available, first-in-class selective human ER partial agonist and small molecule being developed as a treatment for patients with metastatic estrogen receptor-positive breast can...

                          Brand Name : TTC-352

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 15, 2023

                          Lead Product(s) : TTC-352

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : TTC Oncology

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The collaboration will focus on leveraging RADR® AI insights to advance TTC Oncology’s first- and best-in-class drug candidate TTC-352 for recurrent ER+ breast cancer patients and additional patient populations potentially identified by RADR®.

                          Brand Name : TTC-352

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 27, 2023

                          Lead Product(s) : TTC-352

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Lantern Pharma

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Launching of equity crowdfunding campaign, which is providing bridge financing for phase 2 clinical trial. The trial will include validation of biomarker that would predict benefit from TTC-352 therapy.

                          Brand Name : TTC-352

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 20, 2021

                          Lead Product(s) : TTC-352

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : University of Illinois

                          Deal Size : $0.1 million

                          Deal Type : Funding

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Preclinical studies showed that TTC-352, which is a selective human estrogen receptor partial agonist, causes complete tumor regression, but unlike tamoxifen, may pose a reduced risk of uterine cancer development.

                          Brand Name : TTC-352

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 27, 2020

                          Lead Product(s) : TTC-352

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : University of Illinois Chicago

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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