[{"orgOrder":0,"company":"Starpharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"US Patent Issued For DEP\u00ae Cabazitaxel Nanoparticle","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I\/ Phase II","country":"","productType":"Small molecule","productStatus":"Approved","date":"September 2021","year":"2021","type":"Not Applicable","leadProduct":"Cabazitaxel","moa":"Tubulin alpha-4A chain","url1":"","url2":"","graph1":"Oncology","graph2":"Phase II","graph3":"Starpharma","amount2":0,"therapeuticAreaNew":"Oncology","highestDevelopmentStatusNew":"Phase II","highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","productSubType":"","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Starpharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Starpharma \/ Not Applicable"},{"orgOrder":0,"company":"Starpharma","sponsor":"Not 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Pharma"},{"orgOrder":0,"company":"Ever Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"EVER Pharma gains EU marketing authorization for value-added Cabazitaxel","therapeuticArea":"Oncology","highestDevelopmentStatus":"Approved","country":"","productType":"Small molecule","productStatus":"Approved","date":"October 2020","year":"2020","type":"Not Applicable","leadProduct":"Cabazitaxel","moa":"","url1":"","url2":"","graph1":"Technology","graph2":"","graph3":"Ever Pharma","amount2":0,"therapeuticAreaNew":"Technology","highestDevelopmentStatusNew":"","highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","productSubType":"","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Ever Pharma \/ Not Applicable","highestDevelopmentStatusID":"13","companyTruncated":"Ever Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Xencor","sponsor":"Leerink Partners","pharmaFlowCategory":"D","amount":"$201.3 million","upfrontCash":"Undisclosed","newsHeadline":"Xencor Closes Public Offering with Full Exercise of Underwriters' Option","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase II","country":"","productType":"Large molecule","productStatus":"New Molecular Entity","date":"September 2024","year":"2024","type":"Public Offering","leadProduct":"Cabazitaxel","moa":"","url1":"","url2":"","graph1":null,"graph2":null,"graph3":"Xencor","amount2":0.20000000000000001,"therapeuticAreaNew":null,"highestDevelopmentStatusNew":null,"highestDevelopmentShortName":null,"therapeuticAreaShortName":null,"productSubType":"","amount2New":0,"dosageForm":"","sponsorNew":"Xencor \/ Leerink Partners","highestDevelopmentStatusID":null,"companyTruncated":"Xencor \/ Leerink Partners"}]

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                          01

                          Details : Cabazitaxel Intravenous Powder (generic for Jevtana Kit®), is a Microtubule inhibitor, available in the 60mg/1.5mL (40mg/mL) strength used fo the treatment of Prostate cancer.

                          Brand Name : Cabazitaxel-Generic

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 01, 2022

                          Lead Product(s) : Cabazitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Natco Pharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Breckenridge Pharmaceutical

                          02

                          Details : Cabazitaxel intravenous powder of strength 60mg/1.5ml (40mg/ml), is an antineoplastic agent and a microtubule inhibitor used in the treatment of prostate cancer.

                          Brand Name : Cabazitaxel-Generic

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 25, 2022

                          Lead Product(s) : Cabazitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Natco Pharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Breckenridge Pharmaceutical

                          03

                          Lead Product(s) : Cabazitaxel,Prednisone

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Cabazitaxel EVER Pharma in combination with prednisone or prednisolone is indicated for the treatment of patients with metastatic castration resistant prostate cancer.

                          Brand Name : Cabazitaxel EVER Pharma

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 21, 2020

                          Lead Product(s) : Cabazitaxel,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Ever Pharma CB

                          04

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Details : The net proceeds will be used to fund the development of XmAb20717 (vudalimab), a bispecific antibody. It is being evaluated for the treatment of Metastatic Castration-resistant Prostate Cancer.

                          Brand Name : XmAb20717

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 12, 2024

                          Lead Product(s) : Vudalimab,Carboplatin,Cabazitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Leerink Partners

                          Deal Size : $201.3 million

                          Deal Type : Public Offering

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                          05

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Details : The positive interim results are particularly significant given all patients in this cohort had late-stage prostate cancer and had failed multiple anti-cancer treatments (including taxanes), in addition to surgeries and radiation, prior to entering the D...

                          Brand Name : DEP Cabazitaxel

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 27, 2021

                          Lead Product(s) : Cabazitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Details : The composition of matter patent covers a DEP® dendrimer conjugated to multiple cabazitaxel drug molecules via a particular releasable linker. DEP® cabazitaxel is a proprietary nanoparticle version of leading prostate cancer drug cabazitaxel (Jevtana®...

                          Brand Name : DEP Cabazitaxel

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 15, 2021

                          Lead Product(s) : Cabazitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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