Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tyra Biosciences Receives IND Clearance for TYRA-300 in Pediatric Achondroplasia
Details : TYRA-300 is an investigational, oral, FGFR3-selective inhibitor currently in development for the treatment of cancer and skeletal dysplasias, including peidatric achondroplasia.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 28, 2024
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tyra Reports Proof-Of-Concept Data for TYRA-300 in Metastatic Cancer
Details : TYRA-300 is an investigational, oral, FGFR3-selective inhibitor currently in development for the treatment of cancer and skeletal dysplasias, including metastatic urothelial cancer.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 24, 2024
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tyra Biosciences Announces Proof-of-Concept Results for TYRA-300 in Hypochondroplasia
Details : TYRA-300 is an oral, potent FGFR3-selective tyrosine kinase inhibitor developed from compay's SNAP platform for treatment of hypochondroplasia and achondroplasia.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 02, 2024
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : RA Capital Management
Deal Size : $200.0 million
Deal Type : Private Placement
Tyra Biosciences, Inc. Announces $200 Million Private Placement Financing
Details : The net proceeds will be used for the development of TYRA-300 an investigational, oral, FGFR3-selective inhibitor currently in development for the treatment of achondroplasia.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 02, 2024
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : RA Capital Management
Deal Size : $200.0 million
Deal Type : Private Placement
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tyra Receives FDA Rare Pediatric Disease Designation for TYRA-300 in Achondroplasia
Details : TYRA-300 is an investigational, oral, FGFR3-selective inhibitor currently in development for the treatment of cancer and skeletal dysplasias, including achondroplasia.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 01, 2024
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tyra Biosciences Expands Development of TYRA-300, an Oral FGFR3 Selective Agent, into Achondroplasia
Details : TYRA-300 is an investigational, oral, FGFR3-selective inhibitor currently in development for the treatment of cancer and skeletal dysplasias including achondroplasia.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 01, 2023
Lead Product(s) : TYRA-300
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tyra Biosciences Initiates SURF301 Phase 1/2 Clinical Study and Doses First Patient with TYRA-300
Details : TYRA-300 is an FGFR3 selective inhibitor for the treatment of metastatic urothelial carcinoma of the bladder and urinary tract,is developing initially in intrahepatic cholangiocarcinoma.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 29, 2022
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : TYRA-300 is an FGFR3-selective inhibitor designed to be agnostic to the gatekeeper mutation and has demonstrated less hyperphosphatemia mediated by FGFR1 inhibition than pan-FGFR inhibitors in preclinical models.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 05, 2022
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Carlsbad
Deal Size : $100.0 million
Deal Type : Public Offering
Tyra Biosciences Wants to Bank $100 M for an IPO
Details : TYRA-300, a selective inhibitor of FGFR3, for the treatment of FGFR3-driven cancers initially for patients with bladder cancer who are resistant to FGFR therapies. TYRA-300 has demonstrated potency against both wild-type and resistant FGFR3 targets.
Brand Name : TYRA-300
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 20, 2021
Lead Product(s) : TYRA-300
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Carlsbad
Deal Size : $100.0 million
Deal Type : Public Offering
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