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            Details:

            Bimzelx (bimekizumab) is a humanized IgG1 monoclonal antibody that selectively binds to IL-17A, IL-17F and IL-17AF cytokines. It is approved for the treatment of adults with moderate-to-severe hidradenitis suppurativa.

            Lead Product(s): Bimekizumab

            Therapeutic Area: Dermatology Product Name: Bimzelx

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 22, 2024

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            Details:

            Bimzelx (bimekizumab) is an IL-17A and IL-17F inhibitor, which is being evaluated for the treatment of adults with moderate-to-severe hidradenitis suppurativa.

            Lead Product(s): Bimekizumab

            Therapeutic Area: Dermatology Product Name: Bimzelx

            Highest Development Status: Phase III Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 04, 2024

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            Details:

            Bimzelx (bimekizumab) is a humanized IgG1 monoclonal antibody that selectively binds to IL-17A, IL-17F and IL-17AF cytokines. It is being evaluated for the treatment of adults with moderate-to-severe hidradenitis suppurativa.

            Lead Product(s): Bimekizumab

            Therapeutic Area: Dermatology Product Name: Bimzelx

            Highest Development Status: Phase III Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 22, 2024

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            Details:

            Bimzelx (bimekizumab) is a humanized IgG1 monoclonal antibody that selectively binds to IL-17A, IL-17F and IL-17AF cytokines. It is being evaluated for the treatment of adults with moderate-to-severe hidradenitis suppurativa.

            Lead Product(s): Bimekizumab

            Therapeutic Area: Dermatology Product Name: Bimzelx

            Highest Development Status: Phase III Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 08, 2024

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            The net proceeds will be used to the advancement of novel medicines, including IMB1001, a highly promising humanized antibody targeting CD226, for immune-mediated inflammatory diseases (IMIDs).

            Lead Product(s): IMB1001

            Therapeutic Area: Immunology Product Name: IMB1001

            Highest Development Status: Preclinical Product Type: Large molecule

            Recipient: IMIDomics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Financing March 04, 2024

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            Rystiggo (rozanolixizumab) is a humanized IgG4 monoclonal antibody that binds to the neonatal Fc receptor (FcRn) resulting in the reduction of circulating IgG. It is approved by EMA for generalized myasthenia gravis.

            Lead Product(s): Rozanolixizumab

            Therapeutic Area: Immunology Product Name: Rystiggo

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 08, 2024

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            Zilbrysq (zilucoplan) is FDA-approved as the first and only self-administered C5 complement inhibitor indicated for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-AChR antibody positive.

            Lead Product(s): Zilucoplan Sodium

            Therapeutic Area: Immunology Product Name: Zilbrysq

            Highest Development Status: Approved Product Type: Peptide

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 03, 2024

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            Details:

            Zilbrysq (zilucoplan) is a C5 inhibitor peptide drug candidate, which is currently being evaluated for the treatment of patients with AChR antibody-positive generalized myasthenia gravis.

            Lead Product(s): Zilucoplan Sodium

            Therapeutic Area: Immunology Product Name: Zilbrysq

            Highest Development Status: Approved Product Type: Peptide

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 04, 2023

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            Details:

            Bimzelx (bimekizumab) is a humanized monoclonal IgG1 antibody that is designed to selectively inhibit both IL-17A and IL-17F, two key cytokines driving inflammatory processes, received positive CHMP opinion for severe plaque psoriasis.

            Lead Product(s): Bimekizumab

            Therapeutic Area: Dermatology Product Name: Bimzelx

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 14, 2023

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            Details:

            Rystiggo (rozanolixizumab) is an FcRn Binder antibody drug candidate, which is currently being evaluated for the treatment of adult patients with generalized myasthenia gravis.

            Lead Product(s): Rozanolixizumab

            Therapeutic Area: Immunology Product Name: Rystiggo

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 10, 2023

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