Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Umoja Raises $100M Series C to Advance in Vivo CAR-T Therapies
Details : The proceeds from the financing will enable Umoja to advance its vivo CAR T cell therapy pipeline, including its lead CD22 UB-VV400 program in cancer and Large B-cell Lymphoma.
Product Name : UB-VV400
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 14, 2025
Lead Product(s) : UB-VV111
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Umoja Biopharma Receives FDA IND Clearance for UB-VV111 in Blood Cancers
Details : UB-VV111 is a CD19-directed in-situ generated CAR-T cell therapy candidate, which is being evaluated for the treatment of patients with hematologic malignancies.
Product Name : UB-VV111
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
July 31, 2024
Lead Product(s) : UB-VV111
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : UB-VV111
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : AbbVie Inc
Deal Size : $1,440.0 million
Deal Type : Collaboration
AbbVie and Umoja Biopharma Announce Collaboration to Develop Novel CAR-T Cell Therapies
Details : The collaboration aims for Abbvie to focus on the CD19-directed in-situ generated CAR-T cell therapy candidates, which include UB-VV111 for the treatment of hematologic malignancies.
Product Name : UB-VV111
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 01, 2024
Lead Product(s) : UB-VV111
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : AbbVie Inc
Deal Size : $1,440.0 million
Deal Type : Collaboration
Iaso Bio Announces New Development Partnership with Umoja Biopharma for Therapies
Details : IASO Bio will receive exclusive access to Umoja's synthetic cytokine receptor technology for developing two ex vivo iPSC-derived chimeric antigen receptor-bearing cell therapies.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
March 01, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : IASO Bio
Deal Size : Undisclosed
Deal Type : Collaboration
Umoja Biopharma and IASO Biotherapeutics Announce Research Collaboration
Details : The collaboration will focus on bringing off-the-shelf therapies to patients with hematological malignancies, initially acute myeloid leukemia (AML), with a goal of increasing patient accessibility.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 21, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : IASO Bio
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : UB-VV200
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The presentations will highlight Umoja’s complementary cell therapy platforms for in vivo CAR T-cell therapeutics and RACR-induced cytotoxic lymphocytes (iCIL).
Product Name : UB-VV200
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
October 19, 2022
Lead Product(s) : UB-VV200
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : UB-TT170
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Data for UB-TT170, demonstrates the potential for de novo engineering of novel synthetic cytotoxic effector cells that show significant promise as “off the shelf” cancer therapeutics.
Product Name : UB-TT170
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 04, 2022
Lead Product(s) : UB-TT170
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : UB-VV100
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : New data demonstrates Umoja’s synthetic receptor enabled differentiation (ShRED™), UB-VV100 as a novel platform to differentiate and expand progenitor cells and cytotoxic innate lymphocytes using the RACRTM synthetic cytokine receptor system.
Product Name : UB-VV100
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
July 28, 2022
Lead Product(s) : UB-VV100
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : UB-VV100
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Preclinical safety studies completed to-date demonstrate the overall low risk for off target transduction after in vivo administration of UB-VV100 in two animal models, including a model of intranodal delivery.
Product Name : UB-VV100
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 16, 2022
Lead Product(s) : UB-VV100
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : UB-VV100
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Lupagen
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of agreement, both parties will collaborate to evaluate VivoVec delivery using the Side CAR-T™ system. Lupagen will not develop or commercialize the Side CAR-T™ device for the delivery of viral vectors in the field of oncology during ...
Product Name : UB-VV100
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 23, 2022
Lead Product(s) : UB-VV100
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Lupagen
Deal Size : Undisclosed
Deal Type : Collaboration