[{"orgOrder":0,"company":"Umoja Biopharma","sponsor":"MPM Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2020","type":"Series A Financing","leadProduct":"VivoCAR T cells","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Umoja Biopharma","amount2":0.050000000000000003,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"","sponsorNew":"Umoja Biopharma \/ MPM Capital","highestDevelopmentStatusID":"4","companyTruncated":"Umoja Biopharma \/ MPM Capital"},{"orgOrder":0,"company":"Umoja Biopharma","sponsor":"SoftBank Vision","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Series B Financing","leadProduct":"UB-TT170","moa":"Folate receptor alpha","graph1":"Oncology","graph2":"Preclinical","graph3":"Umoja 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Find Clinical Drug Pipeline Developments & Deals by Umoja Biopharma

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration leverages Nona's proprietary fully human-heavy chain-only antibody technology to produce novel in vivo generated CAR-T cell therapy drug candidates for oncology and autoimmunity.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 12, 2024

                          Lead Product(s) : CAR-T Cell-based Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Recipient : Nona Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : UB-VV111 is a CD19-directed in-situ generated CAR-T cell therapy candidate, which is being evaluated for the treatment of patients with hematologic malignancies.

                          Brand Name : UB-VV111

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 31, 2024

                          Lead Product(s) : UB-VV111

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration aims for Abbvie to focus on the CD19-directed in-situ generated CAR-T cell therapy candidates, which include UB-VV111 for the treatment of hematologic malignancies.

                          Brand Name : UB-VV111

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 04, 2024

                          Lead Product(s) : UB-VV111

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : AbbVie Inc

                          Deal Size : $1,440.0 million

                          Deal Type : Collaboration

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : IASO Bio will receive exclusive access to Umoja's synthetic cytokine receptor technology for developing two ex vivo iPSC-derived chimeric antigen receptor-bearing cell therapies.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 03, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : IASO Bio

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the collaboration, Umoja will leverage Ozette Endpoints™ and Ozette Discovery™ to enable both companies' multidisciplinary scientific and bioinformatic teams to collaborate and expand the benefits of CAR T-cell immunotherapy to patients in need...

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 21, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Ozette Technologies

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration will focus on bringing off-the-shelf therapies to patients with hematological malignancies, initially acute myeloid leukemia (AML), with a goal of increasing patient accessibility.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 21, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Sponsor : IASO Bio

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The presentations will highlight Umoja’s complementary cell therapy platforms for in vivo CAR T-cell therapeutics and RACR-induced cytotoxic lymphocytes (iCIL).

                          Brand Name : UB-VV200

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 19, 2022

                          Lead Product(s) : UB-VV200

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : New data demonstrates Umoja’s synthetic receptor enabled differentiation (ShRED™), UB-VV100 as a novel platform to differentiate and expand progenitor cells and cytotoxic innate lymphocytes using the RACRTM synthetic cytokine receptor system.

                          Brand Name : UB-VV100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 28, 2022

                          Lead Product(s) : UB-VV100

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Preclinical safety studies completed to-date demonstrate the overall low risk for off target transduction after in vivo administration of UB-VV100 in two animal models, including a model of intranodal delivery.

                          Brand Name : UB-VV100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 16, 2022

                          Lead Product(s) : UB-VV100

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the terms of agreement, both parties will collaborate to evaluate VivoVec delivery using the Side CAR-T™ system. Lupagen will not develop or commercialize the Side CAR-T™ device for the delivery of viral vectors in the field of oncology during ...

                          Brand Name : UB-VV100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 23, 2022

                          Lead Product(s) : UB-VV100

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Lupagen

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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