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    [{"orgOrder":0,"company":"Upsher-Smith Laboratories","sponsor":"AmbioPharm","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Peptide","year":"2020","type":"Partnership","leadProduct":"Corticotropin","moa":"ACTH","graph1":"Neurology","graph2":"Approved","graph3":"Upsher-Smith Laboratories","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Upsher-Smith Laboratories \/ Upsher-Smith Laboratories","highestDevelopmentStatusID":"12","companyTruncated":"Upsher-Smith Laboratories \/ Upsher-Smith Laboratories"},{"orgOrder":0,"company":"Upsher-Smith Laboratories","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Ramelteon","moa":"Melatonin receptor 1","graph1":"Sleep","graph2":"Approved","graph3":"Upsher-Smith 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Applicable"}]

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                            01

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Everolimus

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Upsher-Smith Expands Rare Disease Portfolio with Launch of Torpenz™ (everolimus) Tablets

                            Details : Torpenz (everolimus) inhibits antigenic and interleukin (IL-2/15) stimulated activation and proliferation of T and B lymphocytes. It is indicated for Tuberous Sclerosis Complex.

                            Brand Name : Torpenz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 05, 2024

                            Lead Product(s) : Everolimus

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Bora Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Bora Pharmaceuticals Completes Acquisition of Upsher-Smith

                            Details : Through the acquisition, Bora will commercialize Amantadine HCl-Generic, which is an NMDA receptor inhibitor. It is indicated for the treatment of influenza A infections and Parkinsonism.

                            Brand Name : Amantadine HCl-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 01, 2024

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Bora Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            03

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Methimazole

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Upsher-Smith Launches Methimazole Tablets, USP

                            Details : Tapazole-Generic (methimazole) is a thyroid peroxidase inhibitor, small molecule drug candidate which is indicated for Graves’ disease with hyperthyroidism or toxic multinodular goiter.

                            Brand Name : Tapazole-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 29, 2024

                            Lead Product(s) : Methimazole

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Bora Pharmaceuticals

                            Deal Size : $210.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            CDMO Bora Pharmaceuticals Buys Generics Manufacturer Upsher-Smith for $210M

                            Details : Bora acquires Upsher-Smith’s product portfolio, including Amantadine hydrochloride for treating influenza A virus infections.

                            Brand Name : Amantadine HCl-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 18, 2024

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Bora Pharmaceuticals

                            Deal Size : $210.0 million

                            Deal Type : Acquisition

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                            05

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Pitavastatin

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Upsher-Smith Launches Pitavastatin Tablets

                            Details : Pitavastatin tablet is a HMG-CoA reductase inhibitor indicated as an adjunctive therapy to diet in Adult patients with primary hyperlipidemia or mixed dyslipidemia.

                            Brand Name : Livalo-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 06, 2023

                            Lead Product(s) : Pitavastatin

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Mesalazine

                            Therapeutic Area : Gastroenterology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Upsher-Smith Expands Generics Portfolio with Launch of Mesalamine Extended-Release Capsules, USP

                            Details : Mesalamine, also known as 5-aminosalicylic acid extended-release capsule is a small molecule, which is indicated for the maintenance of remission of ulcerative colitis in adults.

                            Brand Name : Apriso-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 21, 2023

                            Lead Product(s) : Mesalazine

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Isotretinoin

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Upsher-Smith Launches Isotretinoin Capsules, USP

                            Details : Isotretinoin capsule inhibits sebaceous gland function and keratinization at pharmacologic doses. It is being indicated for the treatment of severe recalcitrant nodular acne.

                            Brand Name : Accutane-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 24, 2023

                            Lead Product(s) : Isotretinoin

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Sumatriptan

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Tonix Pharmaceuticals Holding Corp

                            Deal Size : $25.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Tonix Pharmaceuticals Completes Acquisition of Two FDA-Approved, Marketed Migraine Products

                            Details : Through the acquisition, Tonix gets two FDA approved products including, Zembrace® SymTouch® (sumatriptan injection) and Tosymra® (sumatriptan nasal spray), indicated for the treatment of acute migraine in adults.

                            Brand Name : Zembrace SymTouch

                            Molecule Type : Small molecule

                            Upfront Cash : $22.0 million

                            July 03, 2023

                            Lead Product(s) : Sumatriptan

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Tonix Pharmaceuticals Holding Corp

                            Deal Size : $25.0 million

                            Deal Type : Acquisition

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                            09

                            Upsher-Smith Laboratories

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                            Antibody Engineering
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                            Lead Product(s) : Sumatriptan

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Tonix Pharmaceuticals Holding Corp

                            Deal Size : $25.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Tonix Pharmaceuticals Enters into Agreement to Acquire Two FDA-Approved, Marketed Migraine Products from Upshe...

                            Details : The acquisition of two currently-marketed products Zembrace SymTouch (sumatriptan succinate injection) and Tosymra (sumatriptan nasal spray), complement Tonix’s current intranasal clinical development program of TNX-1900 for migraine prevention.

                            Brand Name : Zembrace SymTouch

                            Molecule Type : Small molecule

                            Upfront Cash : $22.0 million

                            June 26, 2023

                            Lead Product(s) : Sumatriptan

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Tonix Pharmaceuticals Holding Corp

                            Deal Size : $25.0 million

                            Deal Type : Acquisition

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                            10

                            Upsher-Smith Laboratories

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                            Lead Product(s) : Fluphenazine

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Upsher-Smith Launches Fluphenazine Hydrochloride Tablets

                            Details : Fluphenazine hydrochloride Tablets are a generic version of the brand product, Prolixin. Company has launched Fluphenazine Hydrochloride Tablets, USP in four strengths, 1 mg, 2.5 mg, 5 mg, and 10 mg.

                            Brand Name : Prolixin-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 03, 2023

                            Lead Product(s) : Fluphenazine

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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