Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Eflornithine Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Iwilfin (eflornithine) is an ornithine decarboxylase inhibitor used to reduce the risk of relapse in adult and pediatric patients with high-risk neuroblastoma (HRNB).
Product Name : Iwilfin
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 14, 2023
Lead Product(s) : Eflornithine Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eflornithine Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Approves Eflornithine for Adult and Pediatric Patients with High-Risk Neuroblastoma
Details : Iwilfin (eflornithine) is an ornithine decarboxylase inhibitor used to reduce the risk of relapse in adult and pediatric patients with high-risk neuroblastoma (HRNB).
Product Name : Iwilfin
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 14, 2023
Lead Product(s) : Eflornithine Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eflornithine Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Norgine
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Norgine Enter Agreement to Commercialise DFMO in Independent States
Details : DFMO is a repurposed molecule investigated for use as an extended maintenance treatment for high-risk neuroblastoma (HRNB) in paediatric patients with no active disease (NAD) / no evidence of disease (NED) after first line multiagent, multimodality thera...
Product Name : Iwilfin
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 23, 2021
Lead Product(s) : Eflornithine Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Norgine
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Apomorphine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Supernus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Supernus Completes Acquisition of CNS Portfolio from US WorldMeds
Details : This acquisition significantly expands Supernus' business in CNS and increases and diversifies its revenue and earnings streams, while continuing to maintain a strong balance sheet.
Product Name : Apokyn
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 06, 2020
Lead Product(s) : Apomorphine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Supernus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Apomorphine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Supernus Pharmaceuticals
Deal Size : $530.0 million
Deal Type : Acquisition
Supernus to Acquire CNS Portfolio from US WorldMeds
Details : Acquisition adds three products developed and sold in the U.S. market with a late-stage development candidate in the Supernus pipeline: APOKYN ®, MYOBLOC ® XADAGO ® and Apomorphine Infusion Pump.
Product Name : Apokyn
Product Type : Other Small Molecule
Upfront Cash : $300.0 million
April 28, 2020
Lead Product(s) : Apomorphine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Supernus Pharmaceuticals
Deal Size : $530.0 million
Deal Type : Acquisition