Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Virios Therapeutics Completes Enrollment in IMC-2 Phase 2 Long-COVID Study
Details : IMC-2 (combination of valacyclovir and celecoxib) is being evaluated for treatment for managing the fatigue, sleep, and anxiety associated with Long COVID.
Brand Name : IMC-2
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 23, 2024
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Reports Positive Data from Phase 2 Trial of CAN-2409 in Pancreatic Cancer
Details : CAN-2409 (aglatimagene besadenovec) a gene therapy which constructs encoding for thymidine kinase gene. It is being evaluated with valacyclovir for borderline resectable pancreatic adenocarcinoma.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 03, 2024
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Maxim Group
Deal Size : $1.7 million
Deal Type : Public Offering
Virios Therapeutics Announces Closing of $1.7 Million Public Offering for IMC-2 Study
Details : Virios intends to use the net proceeds to commence preparatory activities for its planned IMC-2, which is being evaluated in mid-stage clinical trial studies for the treatment of long-COVID.
Brand Name : IMC-2
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 22, 2024
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Maxim Group
Deal Size : $1.7 million
Deal Type : Public Offering
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Receives FDA Orphan Drug Designation for CAN-2409 in Pancreatic Cancer
Details : CAN-2409 is an investigational replication-defective adenovirus delivering the HSV-tk gene, combined with valacyclovir, being studied for pancreatic cancer treatment.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 11, 2024
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Therapeutics Announces Positive Interim Data from Phase 2 Trial Of Can-2409
Details : CAN-2409 (aglatimagene besadenovec) is an adenoviral replication-defective engineered gene, evaluated with valacyclovir for borderline resectable pancreatic cancer.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 04, 2024
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Virios Plans to Advance IMC-2 Development for Long-COVID Symptoms
Details : IMC-2 (valacyclovir + celecoxib) is in phase 2 trials as a potential treatment for fatigue, sleep, and other symptoms associated with Long COVID.
Brand Name : IMC-2
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 22, 2024
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Virios Aligns with FDA On IMC-2 Development for Long-COVID
Details : IMC-2 (valacyclovir + celecoxib) is in phase 2 trials for treating fatigue and other symptoms of Long Covid, also known as post-acute sequelae of SARS-CoV-2 infection (PASC).
Brand Name : IMC-2
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 02, 2024
Lead Product(s) : Valacyclovir,Celecoxib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Valacyclovir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Hyloris Announces Positive Clinical Study Results for Valacyclovir Oral Suspension (HY-029)
Details : HY-029 (valaciclovir) is a viral dna polymerase inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of Herpes Simplex Infections.
Brand Name : HY-029
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 26, 2023
Lead Product(s) : Valacyclovir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Therapeutics Receives FDA Fast Track Designation for CAN-2409 in Pancreatic Cancer
Details : CAN-2409 (aglatimagene besadenovec) plus valacyclovir is a replication-defective adenovirus that is designed to deliver the herpes simplex virus thymidine kinase (HSV-tk) gene to cancer cells.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 12, 2023
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CAN-2409 (aglatimagene besadenovec) plus valacyclovir is a replication-defective adenovirus that is designed to deliver the herpes simplex virus thymidine kinase (HSV-tk) gene to cancer cells.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 03, 2023
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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