Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Viracta Announces Positive Data from NAVAL-1 Trial and Updated Nana-val Development Plan
Details : Viracta's lead program, Nana-Val evaluates the all-oral combination of nanatinostat & valganciclovir in a Phase 2 clinical trial for the treatment of EBV-positive relapsed/refractory (R/R) lymphoma.
Brand Name : Nana-Val
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 14, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GVO-1102,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
GenVivo Begins Patient Dosing in Phase I/Ib Trial for GEN2 Gene Vector Immunotherapy
Details : GEN2’s dose-escalation trial, GVO-1102 non-replicating immunotherapy vector administered by intravenous infusion with valganciclovir for the treatment of patients suffering from neoplasms.
Brand Name : GVO-1102
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 27, 2024
Lead Product(s) : GVO-1102,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Viracta Reports Positive Results in NAVAL-1 Trial for EBV+ Lymphoma
Details : Viracta’s lead program VRx-3996 combines nanatinostat and valganciclovir in a Phase 2 trial for EBV-positive relapsed/refractory lymphoma, aiming to address unmet patient needs.
Brand Name : VRx-3996
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 15, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Viracta Completes Enrollment in NAVAL-1 Trial for Peripheral T-Cell Lymphoma
Details : Nana-val (nanatinostat with valganciclovir) is an all-oral investigational therapy targeting Epstein-Barr virus (EBV)-associated cancers. It is being evaluated for EBV+ peripheral T-cell lymphoma.
Brand Name : Nana-val
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 29, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rznomics Secures Orphan Drug Designation for RZ-001 in Hepatocellular Carcinoma
Details : RZ-001, which selectively suppresses hTERT expression in cancer cells, is under Phase 1/2 clinical trials combined with valganciclovir for hepatocellular carcinoma.
Brand Name : RZ-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 02, 2024
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Nana-val (nanatinostat in combination with valganciclovir), a first-in-class, all-oral investigational therapy targeting Epstein-Barr virus (EBV)-associated cancers. It is being evaluated for the treatment of EBV-related nasopharyngeal carcinoma.
Brand Name : Nana-val
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 12, 2023
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Nana-val (nanatinostat + valganciclovir) is a combination medicine. Nanatinostat is an orally available histone deacetylase (HDAC) inhibitor. It is being evaluated in phase 1/2 clinical trials for the treatment of Epstein-Barr Virus-positive solid tumors...
Brand Name : Nana-val
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 04, 2023
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rznomics Inc. Secures Fast Track Designation from the U.S. FDA for RZ-001
Details : RZ-001, the RNA replacement enzyme-based cancer gene therapy for the treatment of GBM, targets and cleaves hTERT mRNA and replaces the mRNA with the therapeutic gene RNA.
Brand Name : RZ-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 10, 2023
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Nana-val (nanatinostat) is an oral histone deacetylase inhibitor, selective for specific Class I HDACs isoform. It is currently being investigated in combination with valganciclovir for R/R EBV+ PTCL.
Brand Name : Nana-Val
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 28, 2023
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Nana-val (nanatinostat and valganciclovir) is an orally available histone deacetylase inhibitor. It is selective for specific isoforms of Class I HDACs, which are key to inducing viral genes that are epigenetically silenced in EBV-associated malignancies...
Brand Name : Nana-val
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 19, 2023
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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