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Find Clinical Drug Pipeline Developments & Deals by ValenzaBio

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : VB421 binds to IGF-1R with sub-50 pM potency and possesses favorable biophysical properties that may provide a differentiated product profile relative to other anti-IGF-1R antibodies.

                          Brand Name : VB421

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 31, 2022

                          Lead Product(s) : Lonigutamab

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : VB517 is a fully human mAb with low-picomolar affinity for c-KIT and has demonstrated potent suppression of human mast cell activation in preclinical models. ValenzaBio plans to initiate clinical studies of VB517 in 2023.

                          Brand Name : VB517

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          February 15, 2022

                          Lead Product(s) : VB517

                          Therapeutic Area : Dermatology

                          Highest Development Status : IND Enabling

                          Recipient : Novelty Nobility

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Lead Product(s) : CD19-targeting mAb

                          Therapeutic Area : Immunology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Fidelity Management & Research Company

                          Deal Size : $70.0 million

                          Deal Type : Series A Financing

                          Details : The fundraise will support the advancement and expansion of ValenzaBio’s pipeline toward clinical development, including VB119, anti-CD19 monoclonal antibody for the treatment of membranous nephropathy and VB421, an anti-IGF-1R antibody.

                          Brand Name : VB119

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 08, 2021

                          Lead Product(s) : CD19-targeting mAb

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Fidelity Management & Research Company

                          Deal Size : $70.0 million

                          Deal Type : Series A Financing

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