Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Viracta Therapeutics Announces NAVAL-1 Trial Closure and Strategic Alternatives
Details : Viracta's lead program, Nana-Val evaluates the all-oral combination of nanatinostat & valganciclovir in a Phase 2 clinical trial for the treatment of EBV-positive relapsed/refractory (R/R) lymphoma.
Product Name : Nana-Val
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 26, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Rznomics Secures Expanded Access for Glioblastoma Patients with Novel Therapy
Details : RZ-001 is an anti-HCC activity by suppressing hTERT expression selectively in cancer cells. It is being in combination With valganciclovir for the treatment in 18 and older with Glioblastoma.
Product Name : RZ-001
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
November 25, 2024
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Viracta Announces Positive Data from NAVAL-1 Trial and Updated Nana-val Development Plan
Details : Viracta's lead program, Nana-Val evaluates the all-oral combination of nanatinostat & valganciclovir in a Phase 2 clinical trial for the treatment of EBV-positive relapsed/refractory (R/R) lymphoma.
Product Name : Nana-val
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 14, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : GVO-1102,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GenVivo Begins Patient Dosing in Phase I/Ib Trial for GEN2 Gene Vector Immunotherapy
Details : GEN2’s dose-escalation trial, GVO-1102 non-replicating immunotherapy vector administered by intravenous infusion with valganciclovir for the treatment of patients suffering from neoplasms.
Product Name : GVO-1102
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 27, 2024
Lead Product(s) : GVO-1102,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Viracta Reports Positive Results in NAVAL-1 Trial for EBV+ Lymphoma
Details : Viracta’s lead program VRx-3996 combines nanatinostat and valganciclovir in a Phase 2 trial for EBV-positive relapsed/refractory lymphoma, aiming to address unmet patient needs.
Product Name : Nana-val
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 15, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Viracta Completes Enrollment in NAVAL-1 Trial for Peripheral T-Cell Lymphoma
Details : Nana-val (nanatinostat with valganciclovir) is an all-oral investigational therapy targeting Epstein-Barr virus (EBV)-associated cancers. It is being evaluated for EBV+ peripheral T-cell lymphoma.
Product Name : Nana-val
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 29, 2024
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Rznomics Secures Orphan Drug Designation for RZ-001 in Hepatocellular Carcinoma
Details : RZ-001, which selectively suppresses hTERT expression in cancer cells, is under Phase 1/2 clinical trials combined with valganciclovir for hepatocellular carcinoma.
Product Name : RZ-001
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 02, 2024
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Nana-val (nanatinostat in combination with valganciclovir), a first-in-class, all-oral investigational therapy targeting Epstein-Barr virus (EBV)-associated cancers. It is being evaluated for the treatment of EBV-related nasopharyngeal carcinoma.
Product Name : Nana-val
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 12, 2023
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Rznomics Inc. Secures Fast Track Designation from the U.S. FDA for RZ-001
Details : RZ-001, the RNA replacement enzyme-based cancer gene therapy for the treatment of GBM, targets and cleaves hTERT mRNA and replaces the mRNA with the therapeutic gene RNA.
Product Name : RZ-001
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
October 11, 2023
Lead Product(s) : RZ-001,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Nana-val (nanatinostat) is an oral histone deacetylase inhibitor, selective for specific Class I HDACs isoforms, which induces viral genes that are epigenetically silenced in EBV associated malignancies. It is currently being investigated in combination ...
Product Name : Nana-val
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 01, 2023
Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable