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Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Valneva \/ Not Applicable"},{"orgOrder":0,"company":"Valneva","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Vaccine","year":"2023","type":"Not Applicable","leadProduct":"VLA1553","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Valneva","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Valneva \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Valneva \/ Not Applicable"},{"orgOrder":0,"company":"Valneva","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Vaccine","year":"2023","type":"Not Applicable","leadProduct":"Chikungunya Vaccine","moa":"","graph1":"Infections and 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\/ Not Applicable"},{"orgOrder":0,"company":"Valneva","sponsor":"CEPI","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Vaccine","year":"2024","type":"Funding","leadProduct":"Chikungunya Vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Valneva","amount2":0.040000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.040000000000000001,"dosageForm":"","sponsorNew":"Valneva \/ CEPI","highestDevelopmentStatusID":"10","companyTruncated":"Valneva \/ CEPI"},{"orgOrder":0,"company":"Valneva","sponsor":"LimmaTech Biologics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"SWITZERLAND","productType":"Vaccine","year":"2024","type":"Partnership","leadProduct":"S4V","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase 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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Ixchiq (Chikungunya Vaccine, Live) intramuscular injection is a vaccine indicated for the prevention of disease caused by chikungunya virus (CHIKV) in 18 years and older.

                          Product Name : Ixchiq

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 05, 2025

                          Lead Product(s) : Chikungunya Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Under the agreement, the DoD will purchase Ixiaro (Inactivated Japanese Encephalitis Vaccine) from Valneva. It is being indicated for active immunization for the prevention of disease caused by JEV.

                          Product Name : Ixiaro

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          January 30, 2025

                          Lead Product(s) : Inactivated Japanese Encephalitis Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : U.S. Department of Defense

                          Deal Size : $32.8 million

                          Deal Type : Agreement

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                          03

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Ixchiq (Chikungunya Vaccine, Live) intramuscular injection is a vaccine indicated for the prevention of disease caused by chikungunya virus (CHIKV) in children 1-11 years old.

                          Product Name : Ixchiq

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : Chikungunya Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Ixchiq (Chikungunya Vaccine, Live) Intramuscular Injection is a vaccine indicated for the prevention of disease caused by chikungunya virus (CHIKV) in individuals 18 years of age and older.

                          Product Name : Ixchiq

                          Product Type : Vaccine

                          Upfront Cash : Not Applicable

                          December 02, 2024

                          Lead Product(s) : Chikungunya Vaccine, Live

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Shigella4V2 is a tetravalent bioconjugate vaccine consisting of the O-antigen polysaccharide of Shigella flexneri 2a, 3a, 6 & of S. sonnei, conjugated to the Pa exotoxin A protein as carrier protein.

                          Product Name : Shigella4V2

                          Product Type : Vaccine

                          Upfront Cash : Not Applicable

                          November 13, 2024

                          Lead Product(s) : Shigella4V2

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : LimmaTech Biologics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Shigella4V (S4V) is the world’s most clinically advanced tetravalent bioconjugate shigellosis vaccine candidate, being investigated in 9 month old infants.

                          Product Name : Shigella4V2

                          Product Type : Vaccine

                          Upfront Cash : Not Applicable

                          October 16, 2024

                          Lead Product(s) : Shigella4V2

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : LimmaTech Biologics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The proceeds will fund the development of the Company’s clinical programs, including Ixchiq, the Phase 3 pediatric, and Phase 4 programs for the chikungunya vaccine.

                          Product Name : Ixchiq

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          September 13, 2024

                          Lead Product(s) : Chikungunya Vaccine, Live

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $68.3 million

                          Deal Type : Private Placement

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                          08

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : VLA15, an alum-adjuvanted intramuscular vaccine, which is currently undergoing clinical development for the treatment of Lyme disease.

                          Product Name : VLA15

                          Product Type : Vaccine

                          Upfront Cash : Not Applicable

                          September 03, 2024

                          Lead Product(s) : VLA15

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Pfizer Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The partnership of Limma with Valneva aims to advance the clinical development of Shigella4V (S4V), which is being evaluated in the mid-stage clinical trial studies for the treatment of Shigellosis.

                          Product Name : Shigella4V

                          Product Type : Vaccine

                          Upfront Cash : $10.8 million

                          August 01, 2024

                          Lead Product(s) : S4V

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : LimmaTech Biologics

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          10

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The funding will support trials of Ixchiq Chikungunya Vaccine in vulnerable groups, such as children and pregnant women. It is already approved for use in adults 18 years of age and older.

                          Product Name : Ixchiq

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          July 22, 2024

                          Lead Product(s) : Chikungunya Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : CEPI

                          Deal Size : $41.3 million

                          Deal Type : Funding

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