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[{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Doses First Participants in Phase 1\/2 Clinical Study Evaluating VAX-24 for the Prevention of Invasive Pneumococcal Disease and Pneumonia in Adults","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase I\/ Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"February 2022","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Doses First Participants in Phase 2 Portion of Ongoing VAX-24 Phase 1\/2 Clinical Proof-of-Concept Study in Adults","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase I\/ 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II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"October 2022","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Sutro Biopharma","pharmaFlowCategory":"D","amount":"$157.5 million","upfrontCash":"$157.5 million","newsHeadline":"Sutro Biopharma and Vaxcyte Enter into Option Grant Agreement for the Development and Manufacturing Rights of Cell-Free Extract","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"December 2022","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte\u2019s VAX-24 Granted FDA Breakthrough Therapy Designation for the Prevention of Invasive Pneumococcal Disease in Adults","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"January 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Announces FDA Clearance of Investigational New Drug Application for VAX-24 for the Prevention of Invasive Pneumococcal Disease in Infants","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase I\/ Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"February 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase 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Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Announces FDA Clearance of Investigational New Drug Application for VAX-31 for the Prevention of Invasive Pneumococcal Disease in Adults","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"IND Enabling","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"October 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"IND Enabling"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Sutro Biopharma","pharmaFlowCategory":"D","amount":"$135.0 million","upfrontCash":"$135.0 million","newsHeadline":"Vaxcyte Exercises Option and Enters into Manufacturing Rights Agreement with Sutro Biopharma to Obtain Control Over Manufacturing and Development of Cell-Free Extract for its Vaccine Candidates","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"November 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Doses First Participants in Phase 1\/2 Clinical Study Evaluating VAX-31 for the Prevention of Invasive Pneumococcal Disease in Adults","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase I\/ Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"November 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Provides Clinical and Regulatory Progress Update on Potential Best-in-Class Pneumococcal Conjugate Vaccine (PCV) Franchise","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase I\/ Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"January 2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Completes Enrollment of Phase 1\/2 Study Evaluating VAX-31 for the Prevention of Invasive Pneumococcal Disease (IPD) in Adults Aged 50 and Older","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase I\/ Phase 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Offering","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"January 2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"BofA Securities","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Vaxcyte Announces Commencement of Proposed Public Offering of Common Stock and Pre-Funded Warrants","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"January 2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Vaxcyte","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Vaxcyte Completes Enrollment of Phase 2 Study Evaluating VAX-24 for the Prevention of Invasive Pneumococcal Disease (IPD) in Infants","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Vaccine","productStatus":"New Molecular Entity","date":"March 2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"}]

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            Vaxcyte's VAX-24 is a 24-valent Pneumococcal conjugate vaccine, presently undergoing Phase II clinical trials specifically for infants to treat Invasive Pneumococcal disease.

            Lead Product(s): VAX-24

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-24

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 04, 2024

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            The net proceeds will be used to fund clinical development of the VAX-24, a Phase 3-ready 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine and VAX-31, next-generation 31-valent PCV, adult and pediatric programs.

            Lead Product(s): VAX-24

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-24

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: BofA Securities

            Deal Size: $862.5 million Upfront Cash: Undisclosed

            Deal Type: Public Offering February 02, 2024

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            The net proceeds will be used to fund clinical development of the VAX-24, a Phase 3-ready 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine and VAX-31, next-generation 31-valent PCV, adult and pediatric programs.

            Lead Product(s): VAX-24

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-24

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: BofA Securities

            Deal Size: $750.0 million Upfront Cash: Undisclosed

            Deal Type: Public Offering January 30, 2024

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            The net proceeds will be used to fund clinical development of the VAX-24, a Phase 3-ready 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine and VAX-31, next-generation 31-valent PCV, adult and pediatric programs.

            Lead Product(s): VAX-24

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-24

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: BofA Securities

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Public Offering January 30, 2024

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            VAX-31 is a 31-valent pneumococcal conjugate vaccine (PCV) candidate which is under phase 1/2 clinical trials to prevent invasive pneumococcal disease (IPD), in healthy adults aged 50 and older.

            Lead Product(s): 31-valent Pneumococcal Conjugate Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-31

            Highest Development Status: Phase I/ Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 29, 2024

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            VAX-31 (31 valent pneumococcal conjugate vaccine) is an investigational PCV candidate, designed to prevent invasive pneumococcal disease. It is especially serious in infants, young children, older adults, and those with immune deficiencies or certain chronic health conditions.

            Lead Product(s): 31-valent Pneumococcal Conjugate Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-31

            Highest Development Status: Phase I/ Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 04, 2024

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            Under the agreement, Vaxcyte obtains exclusive rights to independently develop and manufacture cell-free extract, a key component of the company’s 24-valent pneumococcal conjugate vaccine (PCV) franchise which includes VAX-24 and VAX-31.

            Lead Product(s): 24-valent Pneumococcal Conjugate Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-24

            Highest Development Status: Phase II Product Type: Vaccine

            Recipient: Sutro Biopharma

            Deal Size: $135.0 million Upfront Cash: $135.0 million

            Deal Type: Agreement November 27, 2023

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            VAX-31, an investigational 31-valent PCV candidate, is designed to prevent IPD, which is especially serious in infants, young children, older adults, and those with immune deficiencies or certain chronic health conditions.

            Lead Product(s): 31-valent Pneumococcal Conjugate Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-31

            Highest Development Status: Phase I/ Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 09, 2023

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            VAX-31, an investigational 31-valent PCV candidate, is designed to prevent IPD, which is especially serious in infants, young children, older adults, and those with immune deficiencies or certain chronic health conditions.

            Lead Product(s): 31-valent Pneumococcal Conjugate Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-31

            Highest Development Status: IND Enabling Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 19, 2023

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            Details:

            Under the expanded collaboration, Vaxcyte will utilise existing Lonza infrastructure to advance clinical development and commercialization of Vaxcyte’s PCV candidates, VAX-24, a 24-valent pneumococcal conjugate vaccine and VAX-31, in both the adult and pediatric populations.

            Lead Product(s): 24-valent Pneumococcal Conjugate Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: VAX-24

            Highest Development Status: Phase II Product Type: Vaccine

            Recipient: Lonza Group

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Expanded Collaboration October 16, 2023

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