Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Apollomics Announces Positive Data for Vebreltinib in MET Fusion Tumors in Phase 2
Details : APL-101 (vebreltinib) is a small-molecule inhibitor that targets MET tyrosine kinase activity. It is being developed for the treatment of MET Exon 14 skip non-small cell lung cancer.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 13, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Canaccord Genuity
Deal Size : $6.0 million
Deal Type : Private Placement
Apollomics Announces Private Placement Financing and Addition to Board of Directors
Details : Apollomics plans to use proceeds to fund pipeline programs including APL-101, a selective c-Met inhibitor, for treating non-small cell lung cancer and tumors with c-Met alterations.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 08, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Canaccord Genuity
Deal Size : $6.0 million
Deal Type : Private Placement
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Avistone Approves Vebreltinib as First MET-TKI Treatment for Rare Glioma Subtype in China
Details : APL-101 (vebreltinib) is a highly specific cMet inhibitor which is indicated for the treatment of sGBM/IDH mutant glioblastoma with the ZM fusion gene.
Brand Name : PLB1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 25, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Apollomics Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Predicine Collaborates with Apollomics for Lung Cancer Companion Diagnostic
Details : The collaboration seeks to develop PredicineCARE, a blood cfDNA NGS assay to identify NSCLC patients who may benefit from therapy with APL-101 (vebreltinib), a small molecule c-Met inhibitor.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 05, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Apollomics Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : SDIC CS Capital
Deal Size : $140.0 million
Deal Type : Series B Financing
Avistone Biotechnology Announces Closing of Series B Financing
Details : The net proceeds will be used to support clinical research and development of the Avistone pipeline, including PLB1001 (vebreltinib), a small-molecule inhibitor targeting MET tyrosine kinase activity.
Brand Name : PLB1001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 04, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : SDIC CS Capital
Deal Size : $140.0 million
Deal Type : Series B Financing
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-101 (vebreltinib) is a small-molecule inhibitor that targets MET tyrosine kinase activity. It is being developed for the treatment of MET Exon 14 skip non-small cell lung cancer.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 16, 2023
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-101 (vebreltinib) is a highly specific cMet inhibitor which is under phase 2 clinical development in non-small cell lung cancer and other solid tumors with MET dysregulations.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 31, 2023
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Maxpro Capital Acquisition Corp.
Deal Size : $23.6 million
Deal Type : Private Placement
Details : Apollomics will use the financing to advance APL-101 (vebreltinib), a highly specific cMet inhibitor, in non-small cell lung cancer and other solid tumors with cMet dysregulation.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 30, 2023
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Maxpro Capital Acquisition Corp.
Deal Size : $23.6 million
Deal Type : Private Placement
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