Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Ironwood Pharmaceuticals
Deal Size : $1,000.0 million
Deal Type : Acquisition
Ironwood Announces the Completion of Squeeze-Out Merger with VectivBio
Details : Through the acquisition, Ironwood expands its portfolio with the addition of FE203799 (apraglutide), a next-generation, GLP-2 analog in Phase 3 for short bowel syndrome with intestinal failure (SBS-IF).
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : $1,000.0 million
December 12, 2023
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Ironwood Pharmaceuticals
Deal Size : $1,000.0 million
Deal Type : Acquisition
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Ironwood Pharmaceuticals
Deal Size : $1,000.0 million
Deal Type : Acquisition
Details : Through the acquisition, Ironwood expands its portfolio with the addition of FE203799 (apraglutide), a next-generation, GLP-2 analog in Phase 3 for short bowel syndrome with intestinal failure (SBS-IF).
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : $1,000.0 million
May 22, 2023
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Ironwood Pharmaceuticals
Deal Size : $1,000.0 million
Deal Type : Acquisition
Lead Product(s) : Apraglutide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Asahi Kasei Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
VectivBio and Asahi Kasei Pharma Announce the Start of a Phase 1 Study of Apraglutide in Japan
Details : Apraglutide is a novel long-acting glucagon-like peptide-2 analog designed for to increase fluid and nutrient absorption by the remnant intestine of patients who have short bowel syndrome with intestinal insufficiency or intestinal failure.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Not Applicable
March 13, 2023
Lead Product(s) : Apraglutide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Asahi Kasei Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : FE203799 (apraglutide) is an investigational new drug that is a next-generation, long-acting synthetic GLP-2 analog being developed for a range of rare gastrointestinal diseases where GLP-2 can play a central role in addressing disease pathophysiology.
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : Not Applicable
November 03, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $125.0 million
Deal Type : Public Offering
VectivBio Announces Closing of $125 Million Underwritten Offering of Ordinary Shares
Details : VectivBio intends to use the net proceeds from the offering, (i) clinical development and pre-commercialization activities for its lead product FE203799 (apraglutide) and (ii) general corporate purposes, including general and administrative expenses and ...
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : Undisclosed
October 18, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $125.0 million
Deal Type : Public Offering
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $125.0 million
Deal Type : Public Offering
VectivBio Announces Pricing of $125 Million Underwritten Offering of Ordinary Shares
Details : VectivBio intends to use the net proceeds from the offering, (i) clinical development and pre-commercialization activities for its lead product FE203799 (apraglutide) and (ii) general corporate purposes, including general and administrative expenses and ...
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : Undisclosed
October 13, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $125.0 million
Deal Type : Public Offering
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Apraglutide is investigational new drug that is next-generation, long-acting synthetic GLP-2 analog being developed for range of rare gastrointestinal diseases.
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 13, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase I/ Phase II
Sponsor : SVB Securities
Deal Size : $30.0 million
Deal Type : Public Offering
VectivBio Announces Pricing of $30 Million Public Offering of Ordinary Shares
Details : VectivBio intends to use the net proceeds, together with its existing cash and cash equivalents, available for sale and short-term deposits: to fund clinical development and pre-commercialization activities for its lead product candidate FE203799 (Apragl...
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : Undisclosed
June 15, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I/ Phase II
Sponsor : SVB Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Lead Product(s) : Apraglutide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : FE203799 (apraglutide) is a next-generation, synthetic GLP-2 analog rationally designed with the potential to offer an improved safety and efficacy profile relative to other agents in its class and less frequent dosing.
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : Not Applicable
June 02, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Asahi Kasei Pharma
Deal Size : $200.0 million
Deal Type : Licensing Agreement
Details : The company entered into agreement with Asahi Kasei Pharma to develop and commercialize apraglutide, a next-generation, long-acting GLP-2 analog, for the treatment of short bowel syndrome with intestinal failure, steroid-refractory acute graft-versus-hos...
Brand Name : FE203799
Molecule Type : Peptide
Upfront Cash : $30.0 million
March 30, 2022
Lead Product(s) : Apraglutide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Asahi Kasei Pharma
Deal Size : $200.0 million
Deal Type : Licensing Agreement
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