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Ltd","sponsor":"Mundipharma","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"","productType":"Small molecule","year":"2024","type":"Collaboration","leadProduct":"Fluticasone Propionate","moa":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Approved","graph3":"Vectura Ltd","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Aerosol","sponsorNew":"Vectura Ltd \/ Vectura Ltd","highestDevelopmentStatusID":"12","companyTruncated":"Vectura Ltd \/ Vectura Ltd"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Two companies have a collaboration agreement to develop an environmentally friendly propellant for flutiform® (fluticasone propionate/formoterol fumarate) in a pMDI formulation.

                          Brand Name : Flutiform

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 16, 2024

                          Lead Product(s) : Fluticasone Propionate,Formoterol Fumarate

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Recipient : Mundipharma

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Details : Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments, as well as manufacturing a laboratory-scale batch of IHL-216A (Cannabidiol) to support toxicolog...

                          Brand Name : IHL-216A

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 22, 2021

                          Lead Product(s) : Cannabidiol,Isoflurane

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : Incannex Healthcare

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          Details : IPA-001 is inhaled formulation displayed viricidal activity against SARS-CoV2 after 5 minutes contact time. It is purified extracts from a plant source. These extracts contain proteolytic enzymes that have been shown to rapidly inactivate the SARS-CoV-2 ...

                          Brand Name : IPA-001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 06, 2021

                          Lead Product(s) : IPA-001

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Inspira

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          Details : Hikma will immediately resume launch activities of its generic product for Advair Diskus® (Fluticasone Propionate and Salmeterol Inhalation Powder, USP), 100mcg/50mcg and 250mcg/50mcg doses in the US.

                          Brand Name : Fluticasone Propionate/Salmeterol-Generic

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 21, 2021

                          Lead Product(s) : Fluticasone Propionate,Salmeterol Xinafoate

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Sponsor : Hikma Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Details : The new device is an evolution of Vectura’s lever-operated multi-dose (LOMI) device and builds on Vectura and Hikma’s shared experience with the generic Advair Diskus® programme, enabling accelerated development under this agreement.

                          Brand Name : Fluticasone Propionate/Salmeterol-Generic

                          Molecule Type : Small molecule

                          Upfront Cash : $15.0 million

                          December 17, 2020

                          Lead Product(s) : Fluticasone Propionate,Salmeterol Xinafoate

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Sponsor : Hikma Pharmaceuticals

                          Deal Size : $95.0 million

                          Deal Type : Agreement

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                          06

                          Details : This agreement provides an opportunity for Vectura to realise value from its historical research and investment in VR588, whilst expanding its CDMO development services portfolio by supporting the product's further development with Kinaset.

                          Brand Name : VR588

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 30, 2020

                          Lead Product(s) : VR588

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase I

                          Recipient : Kinaset Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          Details : Fluticasone Propionate / Salmeterol or VR315 is a generic, inhaled combination therapy for asthma/COPD delivered using Vectura's proprietary dry powder inhaler and formulation technology.

                          Brand Name : VR315

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 22, 2020

                          Lead Product(s) : Fluticasone Propionate,Salmeterol Xinafoate

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Sponsor : Hikma Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Details : Vectura will support the development of a single use device/formulation combination for evaluation in Phase I of inhaled oxytocin, and then expedite technical transfer to a commercial manufacturer to advance to Phase III and commercial launch.

                          Brand Name : Undisclosed

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          September 14, 2020

                          Lead Product(s) : Oxytocin

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Preclinical

                          Sponsor : Monash University

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          09

                          Details : QVM149 combines the bronchodilation of indacaterol acetate (a LABA) and the antimuscarinic effects of glycopyrronium bromide (a LAMA) with mometasone furoate in a precise once-daily formulation, delivered via the dose-confirming Breezhaler® device.

                          Brand Name : Enerzair Breezhaler

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 07, 2020

                          Lead Product(s) : Indacaterol Acetate,Glycopyrronium Bromide,Mometasone Furoate

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Sponsor : Novartis Pharmaceuticals Corporation

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Details : Aerami will be responsible for the overall development and commercialisation of inhaled imatinib, with Vectura providing development services expertise and a license to its FOX® mesh nebuliser technology.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 08, 2020

                          Lead Product(s) : Imatinib Mesylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Aerami

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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