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Find Clinical Drug Pipeline Developments & Deals by VelosBio

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                          Top Deals by Deal Size (USD bn)

                          01

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : Acquisition strengthens merck’s oncology pipeline with VLS-101, an investigational antibody-drug conjugate to treat hematological malignancies and solid tumors.

                          Product Name : VLS-101

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : $2,750.0 million

                          November 05, 2020

                          Lead Product(s) : VLS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Merck & Co

                          Deal Size : $2,750.0 million

                          Deal Type : Acquisition

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                          02

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : The Phase 2 trial will enroll patients with previously treated solid tumors. Patients will receive VLS-101 2.5 mg/kg intravenously once every three weeks for as long as they are safely benefiting from VLS-101 therapy.

                          Product Name : VLS-101

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          October 19, 2020

                          Lead Product(s) : VLS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : Food and Drug Administration (FDA) has granted the company Fast Track and Orphan Drug designation for VLS-101 for the treatment of patients with mantle cell lymphoma (MCL).

                          Product Name : VLS-101

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          August 31, 2020

                          Lead Product(s) : VLS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : Oversubscribed funding round to advance the development of investigational, first-in-class antibody-drug conjugates and bispecific antibodies targeting ROR1, a novel oncology target, across multiple cancer types.

                          Product Name : VLS-101

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          July 08, 2020

                          Lead Product(s) : VLS-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Matrix Capital Management

                          Deal Size : $137.0 million

                          Deal Type : Series B Financing

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