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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : T-Guard (ricin toxin A conjugated mAB) is designed to reset the body's immune system in life-threatening T cell‒mediated conditions, potentially including prevention of transplant-related rejection, treatment of acute solid-organ rejection, and severe ...

                          Brand Name : T-Guard

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 28, 2022

                          Lead Product(s) : Ricin Toxin A Conjugated Monoclonal Antibodies

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Xenikos B.V

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : VEL-101/FR104 is a novel investigational maintenance immunosuppressive agent being developed for prevention of acute rejection in kidney transplant recipients.

                          Brand Name : VEL-101

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 18, 2022

                          Lead Product(s) : FR104

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : OSE Immunotherapeutics SA

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : VEL-101 (FR104) is a novel investigational maintenance immunosuppressive agent being developed for prevention of acute rejection in kidney transplant recipients.

                          Brand Name : FR104

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 18, 2022

                          Lead Product(s) : VEL-101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Asahi Kasei Pharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration grants Veloxis worldwide rights to develop, manufacture and commercialize FR104, a CD28 antagonist monoclonal antibody fragment, for all transplant indications. OSE Immunotherapeutics retains all rights to develop FR104 in autoimmune di...

                          Brand Name : FR104

                          Molecule Type : Large molecule

                          Upfront Cash : $8.5 million

                          April 26, 2021

                          Lead Product(s) : FR104

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Recipient : OSE Immunotherapeutics SA

                          Deal Size : $393.6 million

                          Deal Type : Collaboration

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