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    [{"orgOrder":0,"company":"VenatoRx Pharmaceuticals","sponsor":"GARDP","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2020","type":"Collaboration","leadProduct":"Cefepime","moa":"Peptidoglycan synthesis","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"VenatoRx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"VenatoRx Pharmaceuticals \/ GARDP","highestDevelopmentStatusID":"10","companyTruncated":"VenatoRx Pharmaceuticals \/ GARDP"},{"orgOrder":0,"company":"VenatoRx Pharmaceuticals","sponsor":"NIAID","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2020","type":"Funding","leadProduct":"Non-beta-lactam antibiotic","moa":"PBP","graph1":"Infections and Infectious 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Diseases","graph2":"Phase III","graph3":"VenatoRx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"VenatoRx Pharmaceuticals \/ Venatorx Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"VenatoRx Pharmaceuticals \/ Venatorx Pharmaceuticals"},{"orgOrder":0,"company":"VenatoRx Pharmaceuticals","sponsor":"Menarini","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Cefepime","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"VenatoRx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"VenatoRx Pharmaceuticals \/ Menarini","highestDevelopmentStatusID":"10","companyTruncated":"VenatoRx Pharmaceuticals \/ Menarini"},{"orgOrder":0,"company":"VenatoRx Pharmaceuticals","sponsor":"Melinta Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Cefepime","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"VenatoRx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"VenatoRx Pharmaceuticals \/ Melinta Therapeutics","highestDevelopmentStatusID":"10","companyTruncated":"VenatoRx Pharmaceuticals \/ Melinta Therapeutics"}]

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                            01

                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Melinta Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Venatorx and Melinta Update on U.S. NDA for Cefepime-Taniborbactam

                            Details : VNRX-5022 (cefepime) & taniborbactam, an investigational beta-lactam/beta-lactamase inhibitor, is under development for treating complicated urinary tract infections and bacterial pneumonia in adults.

                            Brand Name : VNRX-5022

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 23, 2024

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Melinta Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            VenatoRx Pharmaceuticals

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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Menarini

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Venatorx and Menarini Enter Commercial Agreement for Cefepime-Taniborbactam

                            Details : Menarini will acquire rights to commercialize VNRX-5022/VNRX-5133 (cefepime-taniborbactam), an investigational antibiotic for complicated urinary tract infections, in 96 countries.

                            Brand Name : VNRX-5022

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 09, 2024

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Menarini

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            VenatoRx Pharmaceuticals

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : Melinta Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Melinta Therapeutics and Venatorx Pharmaceuticals Announce Licensing Agreement to Commercialize Cefepime-Tanib...

                            Details : The agreement aims to commercialize cefepime-taniborbactam, a beta-lactam inhibitor combination antibiotic being developed for the treatment of complicated UTI and hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia in adu...

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 09, 2023

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : Melinta Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            04

                            VenatoRx Pharmaceuticals

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                            Medlab Asia & Asia Health
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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Ceftibuten-ledaborbactam Etzadroxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : BARDA

                            Deal Size : $167.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Venatorx Pharmaceuticals Awarded a Third Antibiotic BARDA Contract

                            Details : The funding will be used to support the development of oral antibiotic VNRX-7145 (ceftibuten-ledaborbactam etzadroxil) for the treatment of complicated urinary tract infection (cUTI), including pyelonephritis.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 10, 2023

                            Lead Product(s) : Ceftibuten-ledaborbactam Etzadroxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : BARDA

                            Deal Size : $167.0 million

                            Deal Type : Funding

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                            05

                            VenatoRx Pharmaceuticals

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                            Medlab Asia & Asia Health
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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Everest Medicines

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Venatorx Pharmaceuticals Announces FDA Acceptance and Priority Review of New Drug Application for Cefepime-Tan...

                            Details : Cefepime-taniborbactam is an investigational intravenous (IV) beta-lactam/beta-lactamase inhibitor (BL/BLI) antibiotic combination being developed for the treatment of complicated urinary tract infections.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 15, 2023

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Everest Medicines

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            VenatoRx Pharmaceuticals

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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Venatorx Pharmaceuticals to Present at IDWeek 2022

                            Details : VNRX-5133 (cefepime), a fourth-generation cephalosporin, is a widely used beta-lactam (BL) antibiotic with more than two decades of proven safety and clinical utility against susceptible gram-negative and gram-positive bacteria.

                            Brand Name : VNRX-5133

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 19, 2022

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            VenatoRx Pharmaceuticals

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                            Medlab Asia & Asia Health
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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Taniborbactam,Cefepime

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : AMR Action Fund

                            Deal Size : Undisclosed

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Venatorx Pharmaceuticals Raises Series C Financing Led by the AMR Action Fund

                            Details : Proceeds from financing will be used to support Venatorx as it advances its novel antibacterial VNRX-5133, through drug development process, including NDA with the U.S. FDA for cefepime-taniborbactam for the treatment of complicated urinary tract infecti...

                            Brand Name : VNRX-5133

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 04, 2022

                            Lead Product(s) : Taniborbactam,Cefepime

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : AMR Action Fund

                            Deal Size : Undisclosed

                            Deal Type : Series C Financing

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                            08

                            VenatoRx Pharmaceuticals

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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Everest Medicines

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Everest Medicines Announces that Licensing Partner Venatorx Pharmaceuticals Reports Positive Results from Pivo...

                            Details : Cefepime-taniborbactam met primary efficacy endpoint of statistical non-inferiority to meropenem in microbiological intent-to-treat population in 70.0% of cefepime-taniborbactam treated patients and 58.0% of meropenem treated patients.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 10, 2022

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Everest Medicines

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            VenatoRx Pharmaceuticals

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                            Medlab Asia & Asia Health
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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Venatorx Pharmaceuticals to Present Data on Cefepime-Taniborbactam at IDWeek 2020

                            Details : In a 7-day HFIM with humanized exposures and high initial inoculums, Cefepime (FEP)-Taniborbactam (TAN) provided sustained bactericidal activity against multidrug-resistant Enterobacterales and P. aeruginosa strains and suppressed growth of resistant sub...

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 21, 2020

                            Lead Product(s) : Cefepime,Taniborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            VenatoRx Pharmaceuticals

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                            VenatoRx Pharmaceuticals

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                            Lead Product(s) : Non-beta-lactam antibiotic

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Discovery

                            Sponsor : NIAID

                            Deal Size : $44.2 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Venatorx Pharmaceuticals Awarded up to $44.2 Million to Advance Novel Inhibitors of Penicillin Binding Protein...

                            Details : Funding aims to advance a novel series of Penicillin Binding Protein (PBP) Inhibitors targeting multi-drug resistant (MDR) Acinetobacter baumannii through Phase 1 clinical testing.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            July 27, 2020

                            Lead Product(s) : Non-beta-lactam antibiotic

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Discovery

                            Sponsor : NIAID

                            Deal Size : $44.2 million

                            Deal Type : Funding

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