[{"orgOrder":0,"company":"VIB","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"BELGIUM","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Antibody-based drug","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"VIB","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"VIB \/ Not Applicable","highestDevelopmentStatusID":"1","companyTruncated":"VIB \/ Not Applicable"},{"orgOrder":0,"company":"VIB","sponsor":"ExeVir Bio","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2021","type":"Series A Financing","leadProduct":"VHH72-Fc antibody","moa":"SARS-CoV-2 spike protein","graph1":"Infections and Infectious Diseases","graph2":"IND Enabling","graph3":"VIB","amount2":0.050000000000000003,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.050000000000000003,"dosageForm":"Subcutaneous Injection","sponsorNew":"VIB \/ VIB","highestDevelopmentStatusID":"5","companyTruncated":"VIB \/ VIB"},{"orgOrder":0,"company":"VIB","sponsor":"Surface Oncology","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"SRF388","moa":"IL-27","graph1":"Oncology","graph2":"Phase I","graph3":"VIB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"VIB \/ VIB","highestDevelopmentStatusID":"6","companyTruncated":"VIB \/ VIB"},{"orgOrder":0,"company":"VIB","sponsor":"ExeVir Bio","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2023","type":"Not Applicable","leadProduct":"XVR013","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"VIB","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"VIB \/ VIB","highestDevelopmentStatusID":"4","companyTruncated":"VIB \/ VIB"},{"orgOrder":0,"company":"VIB","sponsor":"Oxurion","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"","productType":"Peptide","year":"2023","type":"Licensing Agreement","leadProduct":"THR-149","moa":"","graph1":"Ophthalmology","graph2":"Phase II","graph3":"VIB","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0.029999999999999999,"dosageForm":"Injectable\/Injection","sponsorNew":"VIB \/ VIB","highestDevelopmentStatusID":"8","companyTruncated":"VIB \/ VIB"}]

Find Clinical Drug Pipeline Developments & Deals by VIB

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the agreement, VIB acquired Oxurion's preclinical oncology asset and will use the upfront in the development of THR-149, being evaluated in a Phase 2 clinical trial as a potential treatment for of diabetic macular edema.

                          Brand Name : THR-149

                          Molecule Type : Peptide

                          Upfront Cash : $0.4 million

                          July 24, 2023

                          Lead Product(s) : THR-149

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Recipient : Oxurion

                          Deal Size : $32.4 million

                          Deal Type : Licensing Agreement

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : XVR013 targets a conserved region in the spike S2 subunit that is essential for viral entry. It neutralizes all previous and current variants of concern and the currently most frequently circulating variants, including XBB, XBB.1.5, BQ.1.1 and BF.7.

                          Brand Name : XVR013

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          March 13, 2023

                          Lead Product(s) : XVR013

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : ExeVir Bio

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SRF388 is a fully human anti-IL-27 antibody designed to inhibit the activity of this immunosuppressive cytokine, targets the rate-limiting p28 subunit of IL-27, and preclinical studies have shown that treatment with SRF388 blocks immunosuppressive biolog...

                          Brand Name : SRF388

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 19, 2022

                          Lead Product(s) : SRF388

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Surface Oncology

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Unique llama-derived VHH72-Fc antibody (XVR011) for potential treatment and prevention of Covid-19, ready to start first-in-human trials.

                          Brand Name : XVR011

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          March 16, 2021

                          Lead Product(s) : VHH72-Fc antibody

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Recipient : ExeVir Bio

                          Deal Size : $50.0 million

                          Deal Type : Series A Financing

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The team has now established that the antibody can neutralize a lab variant of the virus, an important step forward in the development of a potential antiviral drug against the new coronavirus.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 16, 2020

                          Lead Product(s) : Antibody-based drug

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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