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    [{"orgOrder":0,"company":"Vicore Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"SWEDEN","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"VP01","moa":"Angiotensin II receptor type 2","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"Vicore Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Vicore Pharma \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Vicore Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Vicore Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SWEDEN","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Buloxibutid","moa":"Angiotensin II receptor type 2","graph1":"Infections and 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Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"SWEDEN","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Buloxibutid","moa":"Angiotensin II receptor type 2","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Vicore Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Vicore Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Vicore Pharma \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Vicore Pharma

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    01

    Vicore Pharma

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore Reports Positive Results from Phase 2a AIR Trial of Buloxibutid in IPF

    Details : C21 (buloxibutid) is an angiotensin II type 2 receptor agonist, which is currently being evaluated for the treatment of patients with idiopathic pulmonary fibrosis.

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    May 20, 2024

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    02

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Endocrinology

    Study Phase : Phase I

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore Initiates Clinical Proof-Of-Concept Study of Endothelial Dysfunction

    Details : C21 is an angiotensin II type 2 receptor agonist, which s being developed for the treatment endothelial dysfunction (reflecting blood vessel health) in patients with type-2-diabetes-mellitus.

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    March 05, 2023

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase I

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore's AIR Study Interim Analysis Suggests that C21 Improves Lung Function in IPF Patients

    Details : With these results, the company initiates the planning of AIR 2, a double-blind controlled phase 2 dose-finding study to confirm these results and accelerate the development of C21 in parallel to completing the AIR trial.

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    October 02, 2022

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Phase II

    Sponsor : Orphan Reach

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore IPF Interim Data Selected as an Oral "Late-breaker" at the ERS Congress

    Details : The AIR trial1 is an open label single arm phase 2 trial in treatment naïve IPF patients in which 100 mg of C21 (VP01) was administered twice daily for 24 weeks with an optional 12-week extension.

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    August 17, 2022

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Phase II

    Sponsor : Orphan Reach

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    05

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    Lead Product(s) : CAS 138564-60-0

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Phase I

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore announces first human dosed with novel ATRAG, C106

    Details : C106 is first of four advanced candidate drugs from VP03 program to enter clinical trials. C106 and the three additional candidates are small molecules with high affinity for AT2R and intended for indications also outside rare lung disease.

    Product Name : C106

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    June 16, 2022

    Lead Product(s) : CAS 138564-60-0

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Phase I

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Vicore Pharma

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore's Digital Therapeutic For IPF Patients Shows Nearly 50% Anxiety Reduction In Pilot Study

    Details : C21 is a small molecule compound, which is in clinical development for the treatment of IPF and COVID-19. The experimental programme will assess the potential of C21 for addressing fibrosis, inflammation and vasculopathy in a variety of diseases such as ...

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    June 10, 2022

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : CAS 138564-60-0

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Preclinical

    Sponsor : Emeriti Bio

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Vicore Takes Major Step Towards a Clinical Platform Company Targeting AT2R – New Molecule Ready for Phase 1

    Details : The first candidate in the VP03 program, new AT2R agonist C106, shows high selectivity for AT2R and good activity in reducing TGFb in human tissue with patent protection to 2041, is ready to enter a phase 1 trial.

    Product Name : C106

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    February 23, 2022

    Lead Product(s) : CAS 138564-60-0

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Preclinical

    Sponsor : Emeriti Bio

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Infections and Infectious Diseases

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lancet's EClinicalMedicine Publishes Phase 2 Data On C21 in COVID-19

    Details : C21 is a first-in-class, orally available, low molecular weight, angiotensin II type 2 receptor (AT2R) agonist that activates the “protective arm” of the renin-angiotensin system (RAS) leading to resolution and regeneration following tissue damage.

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    October 25, 2021

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Vicore Obtains SARS Coronavirus Patent for C21 in The USA

    Details : C21 is first-in-class, orally available, low molecular weight, angiotensin II type 2 receptor agonist. C21 on respiratory function in COVID-19 was documented in recent phase 2 trial showing that C21 reduced need for supplemental oxygen in hospitalized pa...

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    September 22, 2021

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Pulmonary/Respiratory Diseases

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Buloxibutid

    Therapeutic Area : Infections and Infectious Diseases

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Vicore Starts Dosing of First COVID-19 Patients in The Global Phase 3 Trial ATTRACT-3

    Details : ATTRACT-3 is the pivotal trial in which C21, an angiotensin II type 2 receptor (AT2R) agonist, is tested for the treatment of COVID-19. C21 showed significantly reduced the extended need for supplemental oxygen therapy.

    Product Name : C21

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    September 17, 2021

    Lead Product(s) : Buloxibutid

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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