Lead Product(s) : Vidutolimod,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Regeneron Pharmaceuticals
Deal Size : $250.0 million
Deal Type : Acquisition
Regeneron Completes Acquisition of Checkmate Pharmaceuticals
Details : The acquisition strengthens Regeneron's portfolio of immuno-oncology candidates, by acquiring Checkmate's pipeline including lead candidate, CMP-001 (vidutolimod), an advanced generation CpG-A oligodeoxynucleotide Toll-like receptor 9 agonist delivered i...
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : $250.0 million
May 31, 2022
Lead Product(s) : Vidutolimod,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Regeneron Pharmaceuticals
Deal Size : $250.0 million
Deal Type : Acquisition
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : University of Iowa Holden Comprehensive Cancer Center
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The objective of this study is to determine the dose of CMP-001 (vidutolimod) that, in combination with pembrolizumab, has optimal clinical efficacy and acceptable toxicity in patients with relapsed lymphoma who have failed at least one line of therapy.
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 26, 2022
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : University of Iowa Holden Comprehensive Cancer Center
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vidutolimod,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Regeneron Pharmaceuticals
Deal Size : $250.0 million
Deal Type : Acquisition
Details : Regeneron's resources and expertise will help accelerate the development of vidutolimod and realization of the full potential of our virus-like particle (VLP) platform for immunotherapy.
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : $250.0 million
April 19, 2022
Lead Product(s) : Vidutolimod,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Regeneron Pharmaceuticals
Deal Size : $250.0 million
Deal Type : Acquisition
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CMP-001 (vidutolimod), is an advanced generation Toll-like receptor 9 (TLR9) agonist, delivered as a biologic virus-like particle utilizing a CpG-A oligodeoxynucleotide as a key component, designed to trigger the body’s innate immune system.
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 08, 2022
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CMP-001, an advanced generation Toll-like receptor 9 (TLR9) agonist, delivered as a biologic virus-like particle utilizing a CpG-A oligodeoxynucleotide as a key component, designed to trigger body’s innate immune system to attack tumors in combination ...
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vidutolimod,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : XOMA
Deal Size : $32.0 million
Deal Type : Acquisition
Details : Vidutolimod triggers the body’s innate immune system to attack tumors in combination with other therapies. XOMA has acquired all future potential royalties from commercial sales of vidutolimod, which are tiered from high-single to double digits.
Brand Name : CMP-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 15, 2021
Lead Product(s) : Vidutolimod,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : XOMA
Deal Size : $32.0 million
Deal Type : Acquisition
Lead Product(s) : Vidutolimod,Cemiplimab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Checkmate Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Checkmate announced development program expansion of vidutolimod (CMP-001) into non-melanoma skin cancers in combination with Libtayo® (cemiplimab) under a clinical supply agreement with Regeneron Pharmaceuticals, Inc. (“Regeneron”).
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 10, 2021
Lead Product(s) : Vidutolimod,Cemiplimab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Checkmate Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CMP-001 in combination with pembrolizumab continues to demonstrate durable responses in anti-PD-1 refractory melanoma in ongoing trial.
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 09, 2020
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CMP-001 in combination with pembrolizumab continues to demonstrate durable responses in anti-PD-1 refractory melanoma.
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 15, 2020
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : U.S. FDA has granted Fast Track designation to its product candidate, CMP-001, a differentiated Toll-like receptor 9 (TLR9) agonist, in combination with a programmed death receptor 1 (PD-1) blocking antibody (nivolumab or pembrolizumab) for two developme...
Brand Name : CMP-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 27, 2020
Lead Product(s) : Vidutolimod,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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