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    [{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Atlas Venture","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Series A Financing","leadProduct":"VGL101","moa":"TREM2","graph1":"Neurology","graph2":"IND Enabling","graph3":"Vigil Neuroscience","amount2":0.050000000000000003,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0.050000000000000003,"dosageForm":"Implant","sponsorNew":"Vigil Neuroscience \/ Atlas Venture","highestDevelopmentStatusID":"5","companyTruncated":"Vigil Neuroscience \/ Atlas Venture"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Vida Ventures","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Series B Financing","leadProduct":"VGL101","moa":"TREM2","graph1":"Neurology","graph2":"Phase I","graph3":"Vigil Neuroscience","amount2":0.089999999999999997,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.089999999999999997,"dosageForm":"","sponsorNew":"Vigil Neuroscience \/ Vida Ventures","highestDevelopmentStatusID":"6","companyTruncated":"Vigil Neuroscience \/ Vida Ventures"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Morgan Stanley","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Public Offering","leadProduct":"VGL101","moa":"TREM2","graph1":"Neurology","graph2":"Phase I","graph3":"Vigil Neuroscience","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.11,"dosageForm":"","sponsorNew":"Vigil Neuroscience \/ Morgan Stanley","highestDevelopmentStatusID":"6","companyTruncated":"Vigil Neuroscience \/ Morgan Stanley"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Morgan Stanley","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Public Offering","leadProduct":"VGL101","moa":"TREM2","graph1":"Neurology","graph2":"Phase I","graph3":"Vigil Neuroscience","amount2":0.11,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.11,"dosageForm":"","sponsorNew":"Vigil Neuroscience \/ Morgan Stanley","highestDevelopmentStatusID":"6","companyTruncated":"Vigil Neuroscience \/ Morgan Stanley"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"VGL101","moa":"TREM2","graph1":"Neurology","graph2":"Phase I","graph3":"Vigil Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Vigil Neuroscience \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Vigil Neuroscience \/ Not Applicable"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"VGL101","moa":"","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Vigil Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"","sponsorNew":"Vigil Neuroscience \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Vigil Neuroscience \/ Not Applicable"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"VG-3927","moa":"","graph1":"Neurology","graph2":"IND Enabling","graph3":"Vigil Neuroscience","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Vigil Neuroscience \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Vigil Neuroscience \/ Not Applicable"},{"orgOrder":0,"company":"Vigil Neuroscience","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"VGL101","moa":"","graph1":"Rare Diseases and Disorders","graph2":"Phase II","graph3":"Vigil Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Vigil Neuroscience \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Vigil Neuroscience \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Vigil Neuroscience

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                            01

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vigil Neuroscience Receives Positive Opinion from European Medicines Agency on Orphan Drug Designation for VGL...

                            Details : VGL101 is a fully human monoclonal antibody targeting human TREM2, which is responsible for maintaining microglial cell function. TREM2 deficiency is believed to be a driver of certain neurodegenerative diseases.

                            Brand Name : VGL101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 26, 2023

                            Lead Product(s) : VGL101

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VG-3927

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vigil Neuroscience Announces Update on Its Small Molecule Trem2 Agonist Program

                            Details : VG-3927 is designed to act as a molecular glue that potentiates the TREM2 signaling response to natural damage ligands and brain-penetrant small molecule.

                            Brand Name : VG-3927

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 08, 2023

                            Lead Product(s) : VG-3927

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vigil Neuroscience Announces FDA Has Lifted the Partial Clinical Hold on VGL101

                            Details : VGL101 is a fully human monoclonal antibody targeting human TREM2, which is responsible for maintaining microglial cell function. TREM2 deficiency is believed to be a driver of certain neurodegenerative diseases.

                            Brand Name : VGL101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 30, 2023

                            Lead Product(s) : VGL101

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Morgan Stanley

                            Deal Size : $112.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Neurodegenerative Disease Biotech Vigil Neuroscience Sets Terms for $112 Million IPO

                            Details : Its lead candidate, VGL101, is a fully human monoclonal antibody (mAb) that is initially being developed for adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP).

                            Brand Name : VGL101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 03, 2022

                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Morgan Stanley

                            Deal Size : $112.0 million

                            Deal Type : Public Offering

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                            05

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Morgan Stanley

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Neurodegenerative Disease Biotech Vigil Neuroscience Files For a $100 Million IPO

                            Details : Its lead candidate, VGL101, is a fully human monoclonal antibody (mAb) that is initially being developed for adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP).

                            Brand Name : VGL101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 19, 2021

                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Morgan Stanley

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            06

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vigil Neuroscience Announces First Subject Enrolled in a Natural History Study of Patients with Adult-Onset Le...

                            Details : VGL101, a fully human monoclonal antibody agonist targeting triggering receptor expressed on myeloid cells 2 treatment of patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia.

                            Brand Name : VGL101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 15, 2021

                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Vigil Neuroscience

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                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Vida Ventures

                            Deal Size : $90.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Vigil Neuroscience Completes Series B Financing to Advance Pipeline of Microglia-targeted Medicines to Treat N...

                            Details : Series B financing further advance Vigil’s proprietary pipeline of microglia-targeted medicines for the treatment of neurodegeneration which include both a fully human monoclonal antibody, VGL101, and small molecule agonists of triggering receptor on m...

                            Brand Name : VGL101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            August 18, 2021

                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Vida Ventures

                            Deal Size : $90.0 million

                            Deal Type : Series B Financing

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                            08

                            Vigil Neuroscience

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                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Atlas Venture

                            Deal Size : $50.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Vigil Neuroscience Launches with $50 Million in Financing to Develop Microglia-based Therapeutics for Neurodeg...

                            Details : Vigil will use the Series A funds to progress its lead pipeline candidate, a monoclonal antibody TREM2 agonist, through Phase 1 studies, advance their small molecule TREM2 agonist to IND, as well as pursue additional assets to grow the pipeline.

                            Brand Name : VGL101

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 08, 2020

                            Lead Product(s) : VGL101

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Atlas Venture

                            Deal Size : $50.0 million

                            Deal Type : Series A Financing

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