Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Zenocutuzumab,Trastuzumab,Vinorelbine Tartrate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Zenocutuzumab (MCLA-128) in combination with trastuzumab and vinorelbine in patients met primary endpoint of Clinical Benefit Rate at 24 weeks and showed clinically meaningful activity after 3 lines of anti-HER2 therapies including T-DM1.
Brand Name : MCLA-128
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 10, 2021
Lead Product(s) : Zenocutuzumab,Trastuzumab,Vinorelbine Tartrate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Molibresib,Vinorelbine Tartrate
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Targeted Drug Combo Attacks Breast Cancer Brain Metastases in Mice
Details : The two drugs are tubulin inhibitor, vinorelbine, approved by the U.S. Food and Drug Administration (FDA) and available in clinics, and bromodomain inhibitor, I-BET-762, FDA approved for clinical trials.
Brand Name : I-BET-762
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 26, 2020
Lead Product(s) : Molibresib,Vinorelbine Tartrate
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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