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    [{"orgOrder":0,"company":"Visen Pharmaceuticals","sponsor":"Sequoia China","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"","productType":"Peptide","year":"2021","type":"Series B Financing","leadProduct":"Lonapegsomatropin","moa":"","graph1":"Endocrinology","graph2":"Approved","graph3":"Visen Pharmaceuticals","amount2":0.14999999999999999,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Endocrinology","amount2New":0.14999999999999999,"dosageForm":"Injection","sponsorNew":"Visen Pharmaceuticals \/ Sequoia China","highestDevelopmentStatusID":"12","companyTruncated":"Visen Pharmaceuticals \/ Sequoia China"},{"orgOrder":0,"company":"Visen Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Peptide","year":"2021","type":"Not Applicable","leadProduct":"TransCon CNP","moa":"","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Visen 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    Find Clinical Drug Pipeline Developments & Deals by Visen Pharmaceuticals

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                            01

                            Visen Pharmaceuticals

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                            Lead Product(s) : Palopegteriparatide

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VISEN Pharma PaTHway China Trial Achieves Endpoints in Hypoparathyroidism

                            Details : Yorvipath (palopegteriparatide) is a prodrug of PTH 1-34, which is designed to provide normal parathyroid hormone levels. It is approved for the treatment of adults with chronic hypoparathyroidism.

                            Brand Name : Yorvipath

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            August 12, 2024

                            Lead Product(s) : Palopegteriparatide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VISEN's Biologics License Application for Lonapegsomatropin Accepted in China

                            Details : Skytrofa (lonapegsomatropin) delivers unmodified somatropin for treating children with growth failure due to insufficient growth hormone, with its BLA accepted in China.

                            Brand Name : Skytrofa

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 07, 2024

                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : C-type Natriuretic Peptide Prodrug

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Once-Weekly TransCon™ CNP Achieved Primary Efficacy Objective in Accomplish China Phase 2 Trial

                            Details : TransCon CNP (c-type natriuretic peptide prodrug) is a FGFR 3 inhibitor. It is being evaluated for the treatment of children with achondroplasia (ACH) aged 2 to 10 years.

                            Brand Name : TransCon CNP

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            November 16, 2023

                            Lead Product(s) : C-type Natriuretic Peptide Prodrug

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Palopegteriparatide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Double-Blind Period Completes! Primary Endpoint Analysis of Phase 3 Clinical Trial to Be Conducted for China's...

                            Details : TransCon PTH (palopegteriparatide) is designed to restore physiologic levels and activity of parathyroid hormone (PTH) throughout 24 hours per day, thereby addressing full aspects of the HP disease, including normalizing serum and urinary calcium and ser...

                            Brand Name : TransCon PTH

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            January 06, 2023

                            Lead Product(s) : Palopegteriparatide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved

                            Sponsor : Ascendis Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VISEN Discloses 52-week Clinical Results for Its China Phase 3 Trial of Lonapegsomatropin

                            Details : ACP-011 (lonapegsomatropin), a long-acting prodrug of unmodified somatropin is being investigated as a once-weekly injection in children with growth hormone deficiency (GHD) in China.

                            Brand Name : ACP-011

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            November 17, 2022

                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved

                            Sponsor : Ascendis Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VISEN Pharmaceuticals Announces Top-line Results of Phase 3 Trial of Once-Weekly Lonapegsomatropin, Demonstrat...

                            Details : Top-line results of TransCon hGH, from the trial indicate that lonapegsomatropin was well-tolerated and with comparable safety to daily growth hormone. The safety profile of lonapegsomatropin in Chinese children with GHD was consistent.

                            Brand Name : TransCon hGH

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            May 23, 2022

                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

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                            Lead Product(s) : TransCon PTH

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            The First Hormone Replacement Therapy for Hypoparathyroidism in China Obtains IND Approval for Phase III Clini...

                            Details : The primary endpoints of the study include evaluating the safety, tolerability and efficacy of once-daily subcutaneous injection of TransCon™ PTH in adults with HP.

                            Brand Name : TransCon PTH

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            June 02, 2021

                            Lead Product(s) : TransCon PTH

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : TransCon PTH

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Ascendis Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VISEN's TransCon Human Growth Hormone Phase-III Clinical Trial in China Completes Target Patient Recruitment N...

                            Details : The multicenter, randomized, open-label and parallel control study aims to demonstrate noninferiority in annualized height velocity following weekly injections of TransCon hGH compared to once daily dosing of hGH after 52 weeks of treatment in prepuberta...

                            Brand Name : TransCon PTH

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            March 30, 2021

                            Lead Product(s) : TransCon PTH

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Ascendis Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

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                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Sequoia China

                            Deal Size : $150.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            VISEN Pharmaceuticals Closes $150 Million Series B Financing

                            Details : Proceeds of the Series B financing will be used to accelerate the clinical development of the potential best-in-class portfolio drug candidates and to build a strong foundation for commercialization.

                            Brand Name : TransCon hGH

                            Molecule Type : Peptide

                            Upfront Cash : Undisclosed

                            January 09, 2021

                            Lead Product(s) : Lonapegsomatropin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Sequoia China

                            Deal Size : $150.0 million

                            Deal Type : Series B Financing

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                            Lead Product(s) : Natriuretic Peptide, C-Type

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VISEN Pharmaceuticals Receives IND Approval to Initiate Phase 2 Clinical Trial of TransCon ™ CNP in Achondro...

                            Details : China Center for Drug Evaluation (CDE) of National Medical Products Administration (NMPA) has approved VISEN's IND application to conduct a phase 2 clinical trial of TransCon TM C-Type Natriuretic Peptide (CNP) for patients with achondroplasia (ACH).

                            Brand Name : TransCon CNP

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            January 07, 2021

                            Lead Product(s) : Natriuretic Peptide, C-Type

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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