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    [{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Sotorasib","moa":"||RAS-PI3K-alpha","graph1":"Oncology","graph2":"Phase I","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Vividion Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Vividion Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"Undisclosed","moa":"E3 ligase engager","graph1":"Oncology","graph2":"Preclinical","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Vividion Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Vividion Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"Logos Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Series C Financing","leadProduct":"Undisclosed","moa":"KEAP1-Nrf2","graph1":"Oncology","graph2":"Preclinical","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Vividion Therapeutics \/ Logos Capital","highestDevelopmentStatusID":"4","companyTruncated":"Vividion Therapeutics \/ Logos Capital"},{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"Bayer AG","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Acquisition","leadProduct":"Undisclosed","moa":"KEAP1-Nrf2","graph1":"Oncology","graph2":"Preclinical","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Vividion Therapeutics \/ Bayer AG","highestDevelopmentStatusID":"4","companyTruncated":"Vividion Therapeutics \/ Bayer AG"},{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"F. Hoffmann-La Roche","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Collaboration","leadProduct":"Undisclosed","moa":"Nrf2","graph1":"Oncology","graph2":"Preclinical","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Vividion Therapeutics \/ F. Hoffmann-La Roche","highestDevelopmentStatusID":"4","companyTruncated":"Vividion Therapeutics \/ F. Hoffmann-La Roche"},{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"Bayer AG","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"VVD-130037","moa":"KEAP1","graph1":"Oncology","graph2":"Phase I","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Vividion Therapeutics \/ Bayer AG","highestDevelopmentStatusID":"6","companyTruncated":"Vividion Therapeutics \/ Bayer AG"},{"orgOrder":0,"company":"Vividion Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Pembrolizumab","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Vividion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Vividion Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Vividion Therapeutics \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Vividion Therapeutics

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                            01

                            Vividion Therapeutics

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                            Vividion Therapeutics

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                            Lead Product(s) : VVD-159642,Sotorasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vividion Doses First Patient with RAS-PI3K Inhibitor in Phase I

                            Details : VVD-159642 is an investigational oral RAS-PI3Kα inhibitor, which is currently being evaluated for the treatment of RAS-driven cancers.

                            Product Name : VVD-159642

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 03, 2025

                            Lead Product(s) : VVD-159642,Sotorasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Lead Product(s) : VVD-130850,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vividion Starts Phase I Trial of STAT3 Inhibitor in Advanced Solid and Hematologic Tumors

                            Details : VVD-130850 is an investigational oral small molecule STAT3 inhibitor in phase 1 trials with pembrolizumab for advanced solid tumors and hematologic tumors.

                            Product Name : VVD-130850

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 02, 2024

                            Lead Product(s) : VVD-130850,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Vividion Therapeutics

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                            Lead Product(s) : VVD-130037

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Bayer AG

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vividion Therapeutics Starts Phase I Clinical Trial in Advanced Solid Tumors with KEAP1 Activator

                            Details : VVD-130037 is the investigational oral Kelch-like ECH Associated Protein 1 (KEAP1) activator, which is investigated for the treatment of advanced solid tumors.

                            Product Name : VVD-130037

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 18, 2023

                            Lead Product(s) : VVD-130037

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Bayer AG

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Vividion Therapeutics

                            U.S.A arrow
                            MAGHREB PHARMA
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                            Vividion Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Vividion Therapeutics Earns First Milestone Payment for Advancement of Program Addressing High Value Oncology ...

                            Details : The payment follows Vividion’s completion of a preclinical data package for a program addressing a well-known, but difficult to drug target, for the potential treatment of oncology indications.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $135.0 million

                            June 24, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Bayer AG

                            Deal Size : $2,000.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Bayer Strengthens Drug Discovery Platform Through Acquisition of Vividion Therapeutics

                            Details : Following closing of the acquisition, Bayer will own full rights to Vividion’s proprietary discovery platform, which comprises three integrated, synergistic components: a novel chemoproteomic screening technology, an integrated data portal, and a propr...

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $1,500.0 million

                            May 08, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Bayer AG

                            Deal Size : $2,000.0 million

                            Deal Type : Acquisition

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                            06

                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Vividion Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Logos Capital

                            Deal Size : $135.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Vividion Announces $135 Million Series C Financing to Fuel Broad Pipelineof Precision Oncology and Immunology ...

                            Details : Vividion’s initial wave of wholly owned assets includes programs targeting the KEAP1-NRF2 axis, with antagonists for the treatment of NRF2 mutant and NRF2 addicted cancers, as well as agonists for the treatment of inflammatory diseases.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            February 24, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Logos Capital

                            Deal Size : $135.0 million

                            Deal Type : Series C Financing

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                            07

                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Vividion Therapeutics

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                            MAGHREB PHARMA
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vividion Therapeutics to Present Data on Novel Covalent E3 Ligase Engager Supporting Broad Targeted Protein De...

                            Details : First reported E3 ligase beyond Cereblon and VHL shown to support broad targeted protein degradation of multiple targets in vivo.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            May 15, 2020

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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