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Find Clinical Drug Pipeline Developments & Deals for Vocacapsaicin

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                          01

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : CA-008 (vocacapsaicin) a water-soluble prodrug of capsaicin, rapidly releases capsaicin at surgical site triggering the activation of the TRPV1 receptor on pain-specific nerves, producing analgesia.

                          Brand Name : CA-008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 06, 2024

                          Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The pilot study showed that vocacapsaicin, administered during surgery at a dose of 24 mg (0.3 mg/mL solution), reduced pain after coughing by 46% compared to the placebo control during the first 96 hours after surgery (p=0.02).

                          Brand Name : CA-008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 30, 2022

                          Lead Product(s) : Vocacapsaicin

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The company has entered into a formal agreement with Evolution Research Group (ERG), a leading postsurgical pain clinical research site network in the U.S., to conduct its registration trials with CA-008 (vocacapsaicin).

                          Brand Name : CA-008

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 02, 2022

                          Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Evolution Research Group

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : URMC will participate in the vocacapsaicin Phase 3 clinical trials and develop innovative methods to capture vocacapsaicin’s benefit to patient recovery and rehabilitation.

                          Brand Name : CA-008

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 02, 2022

                          Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : University of Rochester Medical Center

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Concentric intends to use the proceeds from the financing to further fund Phase 3 development activities for vocacapsaicin, its lead therapeutic candidate for postsurgical pain.

                          Brand Name : CA-008

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 26, 2022

                          Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $20.0 million

                          Deal Type : Financing

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