Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Not Applicable
Deal Type : Not Applicable
Notable Labs Receives FDA Clearance to Proceed Further with Volasertib Phase 2 Study
Details : NBL-001 (volasertib) is a PLK-1 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of relapsed/refractory acute myeloid leukemia.
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 24, 2024
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Not Applicable
Deal Type : Not Applicable
Notable Advances in Volasertib Phase 2 Program Using Precision Medicine for Enrollment
Details : NBL-001 (volasertib) is a PLK-1 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of relapsed/refractory acute myelogenous leukemia.
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 22, 2024
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Notable Labs
Deal Size : Undisclosed
Deal Type : Merger
Notable Labs Closes Merger Transaction with VBL Therapeutics
Details : The Merger will focus on developing new precision medicines through Notable’s proprietary Predictive Precision Medicines Platform. NBL-001 (volasertib) is derived from PPMP and is a highly potent PLK1 inhibitor inducing cell cycle arrest and apoptosis ...
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 16, 2023
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Notable Labs
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Notable stockholders Builders VC
Deal Size : $10.3 million
Deal Type : Private Placement
Notable Labs Closes Merger Transaction with VBL Therapeutics
Details : The Merger will create a company developing new precision medicines through Notable’s proprietary Predictive Precision Medicines Platform (PPMP). NBL-001 (volasertib) is derived from PPMP and is a highly potent PLK1 inhibitor inducing cell cycle arrest...
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 16, 2023
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Notable stockholders Builders VC
Deal Size : $10.3 million
Deal Type : Private Placement
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : VBL Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
VBL Therapeutics and Notable Labs Announce Definitive Merger Agreement
Details : The Merger will create a clinical-stage therapeutic platform company developing new precision medicines through Notable’s proprietary PPMP. NBL-001 (volasertib) is derived from PPMP and is a highly potent PLK1 inhibitor inducing cell cycle arrest and a...
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 23, 2023
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : VBL Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Builders VC
Deal Size : $10.3 million
Deal Type : Private Placement
VBL Therapeutics and Notable Labs Announce Definitive Merger Agreement
Details : Notable’s lead asset derived from PPMP is NBL-001 (volasertib), a highly potent PLK1 inhibitor proven to induce cell cycle arrest and apoptosis in various cancer cells.
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 23, 2023
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Builders VC
Deal Size : $10.3 million
Deal Type : Private Placement
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Oncoheroes Biosciences Inc.
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of this agreement, Oncoheroes will retain the license for the development and commercialization of volasertib for pediatric cancers and continue its commitment towards childhood cancer.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 11, 2021
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Oncoheroes Biosciences Inc.
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Volasertib,Cytarabine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Volasertib is a Polo-like kinase 1 (PLK-1) inhibitor with demonstrated activity in AML and other tumor types with significant unmet medical need. Company plan to fast-track volasertib’s development with phase 2/3 clinical trials in AML and other cancer...
Brand Name : NBL-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 11, 2021
Lead Product(s) : Volasertib,Cytarabine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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