Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : VCAR33
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $55.6 million
Deal Type : Private Placement
Vor Bio Announces $55.6 Million Private Placement
Details : Vor Bio will use the net proceeds to fund the clinical and preclinical development of its pipeline candidates, including VCAR33, which is being evaluated for the treatment of relapsed/refractory AML.
Product Name : VCAR33
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 27, 2024
Lead Product(s) : VCAR33
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $55.6 million
Deal Type : Private Placement
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Vor Bio Shares Clinical Update on Shielded Transplants and FDA Support for Trial Design
Details : VOR33 (trem-cel) followed by Mylotarg is being investigated in patients with relapsed/refractory acute myeloid leukemia.
Product Name : VOR33
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
December 09, 2024
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : VCAR33
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Vor Bio Doses First AML Patient with VCAR33 (ALLO) and Provides Corporate Update
Details : VCAR33 is a CD33-directed CAR-T cell therapy made from healthy donor cells, under phase 1/2 development for treating relapsed/refractory acute myeloid leukemia.
Product Name : VCAR33
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 17, 2024
Lead Product(s) : VCAR33
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tremtelectogene Empogeditemcel,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Trem-cel (tremtelectogene empogeditemcel), is a genome-edited hematopoietic stem and progenitor allogeneic donor product candidate in order to remove the CD33 surface target protecting them from a targeted therapy post-transplant.
Product Name : Trem-cel
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 16, 2023
Lead Product(s) : Tremtelectogene Empogeditemcel,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Vor Bio to Present Clinical Data from First Patient Treated with Trem-cel at 2023 Tandem Meetings
Details : VOR33 (trem-cel) is our lead eHSC product candidate created by genetically modifying healthy donor HSCs in order to remove the CD33 surface target which is involved in causing AML and other blood related cancers thus, protecting them from a targeted ther...
Product Name : VOR33
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 19, 2023
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VOR33 (Engineered Hematopoietic Stem Cell) is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell therapy product that lacks the CD33 myeloid protein.
Product Name : VOR33
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
November 10, 2022
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The pre-clinical data of VOR33 (Engineered Hematopoietic Stem Cell), demonstrates that multiplex deletion by CRISPR/Cas9 of CD33 and CLL-1 from human CD34+ HSPCs maintained cell function and persisted long-term post engraftment in vivo.
Product Name : VOR33
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
October 06, 2022
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tremtelectogene Empogeditemcel,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Evercore Group L.L.C.
Deal Size : $65.8 million
Deal Type : Public Offering
Details : Vor Bio intends to use the net proceeds from the offering and concurrent private placement primarily to fund the continued clinical development of Trem-cel (tremtelectogene empogeditemcel) and pipeline products and for working capital and general corpora...
Product Name : Trem-cel
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 12, 2022
Lead Product(s) : Tremtelectogene Empogeditemcel,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Evercore Group L.L.C.
Deal Size : $65.8 million
Deal Type : Public Offering
Lead Product(s) : Tremtelectogene Empogeditemcel,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $50.0 million
Deal Type : Private Placement
Details : Vor Bio intends to use the net proceeds from the offering and concurrent private placement primarily to fund the continued clinical development of Trem-cel (Tremtelectogene Empogeditemcel) and pipeline products and for working capital and general corpora...
Product Name : Trem-cel
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 12, 2022
Lead Product(s) : Tremtelectogene Empogeditemcel,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $50.0 million
Deal Type : Private Placement
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Tremtelectogene empogeditemcel (trem-cel), formerly VOR33, is a genome-edited hematopoietic stem and progenitor allogeneic donor product candidate where CD33 has been deleted using genome engineering.
Product Name : VOR33
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
July 12, 2022
Lead Product(s) : VOR33,Gemtuzumab Ozogamicin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable