Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Aprepitant
Therapeutic Area : Dermatology
Study Phase : Phase II
Recipient : Hoth Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims at activation of Washington University School of Medicine as the first clinical site in the CLEER-001 Phase 2a clinical trial of HT-001 (aprepitant) for the treatment for rash and skin disorders associated with EGFR inhibitor thera...
Brand Name : HT-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 08, 2023
Lead Product(s) : Aprepitant
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Recipient : Hoth Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Motixafortide,Natalizumab
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Recipient : BioLineRx
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The aim of the collaboration is to advance a Phase 1 clinical trial that will evaluate the safety and feasibility of BL-8040 (motixafortide) to mobilize CD34+ hematopoietic stem cells (HSCs) for gene therapies in sickle cell disease (SCD).
Brand Name : BL-8040
Molecule Type : Peptide
Upfront Cash : Undisclosed
March 06, 2023
Lead Product(s) : Motixafortide,Natalizumab
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Recipient : BioLineRx
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration strategically combines Washington University scientists’ expertise in the fundamental and clinical research in neurodegenerative diseases, such as dementia, with Eisai’s extensive experience in drug discovery and development.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
December 14, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : BostonGene
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Study finds that tumor behavior specificities linked with patient responses, and the MxIF analyses identified 14 unique cellular neighborhoods in multi-region tumors that can be utilized to optimize treatment strategies for patients with ccRCC.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
October 04, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : BostonGene
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BBV154
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Recipient : Ocugen
Deal Size : Undisclosed
Deal Type : Agreement
Details : Ocugen’s intranasal vaccine candidate BBV154, is a recombinant, replication-deficient, adenovirus-vectored vaccine with a prefusion stabilized spike protein. In addition, intranasal delivery provides an alternative to those who are hesitant to receive ...
Brand Name : BBV154
Molecule Type : Vaccine
Upfront Cash : Undisclosed
September 28, 2022
Lead Product(s) : BBV154
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Recipient : Ocugen
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Bomedemstat,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Imago BioSciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A combination of IMG-7289 (bomedemstat), in solid tumors enhances their immunogenicity, and atezolizumab, a checkpoint inhibitor, represents in lung cancer treatment, may provide long-term disease management possibilities for patients with small cell lun...
Brand Name : IMG-7289
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 09, 2022
Lead Product(s) : Bomedemstat,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Imago BioSciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tixagevimab,Cilgavimab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Recipient : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : New preclinical authentic ‘live’ virus data demonstrated that EVUSHELD retains potent neutralizing activity against emerging and highly transmissible Omicron SARS-CoV-2 BA.2 subvariant. The data also showed that EVUSHELD retains activity against Omic...
Brand Name : Evusheld
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 21, 2022
Lead Product(s) : Tixagevimab,Cilgavimab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Recipient : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HT-ALZ
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Hoth Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : This Sponsored Research Agreement with Washington University in St. Louis aims to support the continued research and development of HT-ALZ, a novel therapeutic for the treatment of symptoms related to Alzheimer's disease.
Brand Name : HT-ALZ
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 07, 2021
Lead Product(s) : HT-ALZ
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Hoth Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : UltraPorator system is an exclusive device and proprietary software solution for the scale-up of rapid and cost-effective, decentralized manufacturing of UltraCAR-T therapies.
Brand Name : PRGN-3005 UltraCAR-T
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 16, 2020
Lead Product(s) : Covid 19 vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Bharat Biotech
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : This vaccine expands Bharat’s portfolio of vaccines that are currently being developed and are in various stages of clinical development including COVAXIN® which is currently in Phase II human clinical trials in India.
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Undisclosed
September 23, 2020
Lead Product(s) : Covid 19 vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Bharat Biotech
Deal Size : Undisclosed
Deal Type : Licensing Agreement
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