[{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Bharat Biotech","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2020","type":"Licensing Agreement","leadProduct":"Covid 19 vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intranasal","sponsorNew":"Washington University School of Medicine \/ Bharat Biotech","highestDevelopmentStatusID":"4","companyTruncated":"Washington University School of Medicine \/ Bharat Biotech"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Precigen","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"PRGN-3005","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Washington University School of Medicine \/ Washington University School of Medicine","highestDevelopmentStatusID":"6","companyTruncated":"Washington University School of Medicine \/ Washington University School of Medicine"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Hoth Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2021","type":"Agreement","leadProduct":"HT-ALZ","moa":"Amyloid beta protein","graph1":"Neurology","graph2":"Preclinical","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Washington University School of Medicine \/ Hoth Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Washington University School of Medicine \/ Hoth Therapeutics"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"AstraZeneca","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Cilgavimab","moa":"SARS-CoV-2 spike protein","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Washington University School of Medicine \/ Washington University School","highestDevelopmentStatusID":"12","companyTruncated":"Washington University School of Medicine \/ Washington University School"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Imago BioSciences","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Bomedemstat","moa":"LSD1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Washington University School of Medicine \/ University of Washington School of Medicine","highestDevelopmentStatusID":"7","companyTruncated":"Washington University School of Medicine \/ University of Washington School of Medicine"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Ocugen","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2022","type":"Agreement","leadProduct":"BBV154","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Spray","sponsorNew":"Washington University School of Medicine \/ Washington University","highestDevelopmentStatusID":"12","companyTruncated":"Washington University School of Medicine \/ Washington University"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"BostonGene","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Undisclosed","year":"2022","type":"Not Applicable","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Washington University School of Medicine \/ Washington University School of Medicine","highestDevelopmentStatusID":"4","companyTruncated":"Washington University School of Medicine \/ Washington University School of Medicine"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Eisai","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Undisclosed","year":"2022","type":"Collaboration","leadProduct":"Undisclosed","moa":"","graph1":"Neurology","graph2":"Discovery","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Washington University School of Medicine \/ Washington University School of Medicine","highestDevelopmentStatusID":"2","companyTruncated":"Washington University School of Medicine \/ Washington University School of Medicine"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"BioLineRx","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Peptide","year":"2023","type":"Collaboration","leadProduct":"Motixafortide","moa":"","graph1":"Hematology","graph2":"Phase I","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Washington University School of Medicine \/ Washington University School of Medicine","highestDevelopmentStatusID":"6","companyTruncated":"Washington University School of Medicine \/ Washington University School of Medicine"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Hoth Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"Aprepitant","moa":"","graph1":"Dermatology","graph2":"Phase II","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Gel","sponsorNew":"Washington University School of Medicine \/ Washington University School of Medicine","highestDevelopmentStatusID":"8","companyTruncated":"Washington University School of Medicine \/ Washington University School of Medicine"}]

Find Clinical Drug Pipeline Developments & Deals by Washington University School of Medicine

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The collaboration aims at activation of Washington University School of Medicine as the first clinical site in the CLEER-001 Phase 2a clinical trial of HT-001 (aprepitant) for the treatment for rash and skin disorders associated with EGFR inhibitor thera...

                          Brand Name : HT-001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 08, 2023

                          Lead Product(s) : Aprepitant

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Recipient : Hoth Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The aim of the collaboration is to advance a Phase 1 clinical trial that will evaluate the safety and feasibility of BL-8040 (motixafortide) to mobilize CD34+ hematopoietic stem cells (HSCs) for gene therapies in sickle cell disease (SCD).

                          Brand Name : BL-8040

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          March 06, 2023

                          Lead Product(s) : Motixafortide,Natalizumab

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Recipient : BioLineRx

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The collaboration strategically combines Washington University scientists’ expertise in the fundamental and clinical research in neurodegenerative diseases, such as dementia, with Eisai’s extensive experience in drug discovery and development.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 14, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Discovery

                          Recipient : Eisai

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Study finds that tumor behavior specificities linked with patient responses, and the MxIF analyses identified 14 unique cellular neighborhoods in multi-region tumors that can be utilized to optimize treatment strategies for patients with ccRCC.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Not Applicable

                          October 04, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : BostonGene

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Ocugen’s intranasal vaccine candidate BBV154, is a recombinant, replication-deficient, adenovirus-vectored vaccine with a prefusion stabilized spike protein. In addition, intranasal delivery provides an alternative to those who are hesitant to receive ...

                          Brand Name : BBV154

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          September 28, 2022

                          Lead Product(s) : BBV154

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Recipient : Ocugen

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : A combination of IMG-7289 (bomedemstat), in solid tumors enhances their immunogenicity, and atezolizumab, a checkpoint inhibitor, represents in lung cancer treatment, may provide long-term disease management possibilities for patients with small cell lun...

                          Brand Name : IMG-7289

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 09, 2022

                          Lead Product(s) : Bomedemstat,Atezolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Imago BioSciences

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : New preclinical authentic ‘live’ virus data demonstrated that EVUSHELD retains potent neutralizing activity against emerging and highly transmissible Omicron SARS-CoV-2 BA.2 subvariant. The data also showed that EVUSHELD retains activity against Omic...

                          Brand Name : Evusheld

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 21, 2022

                          Lead Product(s) : Tixagevimab,Cilgavimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Recipient : AstraZeneca

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : This Sponsored Research Agreement with Washington University in St. Louis aims to support the continued research and development of HT-ALZ, a novel therapeutic for the treatment of symptoms related to Alzheimer's disease.

                          Brand Name : HT-ALZ

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 07, 2021

                          Lead Product(s) : HT-ALZ

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Hoth Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          09

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : UltraPorator system is an exclusive device and proprietary software solution for the scale-up of rapid and cost-effective, decentralized manufacturing of UltraCAR-T therapies.

                          Brand Name : PRGN-3005 UltraCAR-T

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 16, 2020

                          Lead Product(s) : PRGN-3005

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Precigen

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : This vaccine expands Bharat’s portfolio of vaccines that are currently being developed and are in various stages of clinical development including COVAXIN® which is currently in Phase II human clinical trials in India.

                          Brand Name : Undisclosed

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          September 23, 2020

                          Lead Product(s) : Covid 19 vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Bharat Biotech

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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