[{"orgOrder":0,"company":"Weill Cornell Medicine","sponsor":"Hoth Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2021","type":"Expanded Collaboration","leadProduct":"HT-003","moa":"TLR2","graph1":"Dermatology","graph2":"Preclinical","graph3":"Weill Cornell Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical","sponsorNew":"Weill Cornell Medicine \/ Hoth Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Weill Cornell Medicine \/ Hoth Therapeutics"},{"orgOrder":0,"company":"Weill Cornell Medicine","sponsor":"Akelos","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Undisclosed","year":"2021","type":"Not Applicable","leadProduct":"AKE-1018","moa":"HCN1 channel","graph1":"Neurology","graph2":"Preclinical","graph3":"Weill Cornell Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Weill Cornell Medicine \/ Weill Cornell Medicin","highestDevelopmentStatusID":"4","companyTruncated":"Weill Cornell Medicine \/ Weill Cornell Medicin"},{"orgOrder":0,"company":"Weill Cornell Medicine","sponsor":"AffyImmune Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"AIC100","moa":"ICAM-1","graph1":"Oncology","graph2":"Phase I","graph3":"Weill Cornell Medicine","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Weill Cornell Medicine \/ Weill Medical College of Cornell University","highestDevelopmentStatusID":"6","companyTruncated":"Weill Cornell Medicine \/ Weill Medical College of Cornell University"}]

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The FDA's Fast Track designation is designed for AIC100 facilitate development and expedite review of drug candidates to treat serious conditions and address an unmet medical need.

                          Brand Name : AIC100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 17, 2021

                          Lead Product(s) : AIC100

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : AffyImmune Therapeutics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Akelos's oral lead compound AKE-1018, at 10-times the lowest effective antihyperalgesic dose tested, does not affect heart rate, blood pressure, motor strength/coordination, is non-sedating, and lacks the potential for abuse.

                          Brand Name : AKE-1018

                          Molecule Type : Undisclosed

                          Upfront Cash : Not Applicable

                          March 04, 2021

                          Lead Product(s) : AKE-1018

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Recipient : Akelos

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The 1-year agreement extension is based on positive results generated from the prior research agreement that support a therapeutic effect of HT-003 in key signaling pathways contributing to the development of acne.

                          Brand Name : HT-003

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 28, 2021

                          Lead Product(s) : HT-003

                          Therapeutic Area : Dermatology

                          Highest Development Status : Preclinical

                          Sponsor : Hoth Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Expanded Collaboration

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